Mismatch Repair Deficiency and Microsatellite Instability

Mismatch repair deficiency (MMRd) is caused by the biallelic inactivation of an MMR gene, which can be attributed either to an inherited or an acquired pathway. MMRd is characterized by the inability of cells to repair spontaneous mutations in microsatellites that occur during replication. Microsate...

詳細記述

書誌詳細
主要な著者: Sandra Schöniger, Josef Rüschoff
フォーマット: 論文
言語:English
出版事項: MDPI AG 2022-08-01
シリーズ:Encyclopedia
主題:
オンライン・アクセス:https://www.mdpi.com/2673-8392/2/3/106