Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics

Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics

Abstract Naturally occurring canine cancers have remarkable similarities to their human counterparts. To better understand these similarities, we investigated 671 client-owned dogs from 96 breeds with 23 common tumor types, including those whose mutation profile are unknown (anal sac carcinoma and n...

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Manylion Llyfryddiaeth
Prif Awduron: Lucas Rodrigues, Joshua Watson, Yuan Feng, Benjamin Lewis, Garrett Harvey, Gerald Post, Kate Megquier, Michelle E. White, Lindsay Lambert, Aubrey Miller, Christina Lopes, Shaying Zhao
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Nature Portfolio 2023-07-01
Cyfres:Scientific Reports
Mynediad Ar-lein:https://doi.org/10.1038/s41598-023-37505-2

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https://doi.org/10.1038/s41598-023-37505-2

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