Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report
Deep brain stimulation of the anterior nucleus of the thalamus is an effective treatment for patients with refractory epilepsy who do not respond sufficiently to medical therapy. Optimal therapeutic effects of deep brain stimulation probably depend on accurate positioning of the stimulating electrod...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-06-01
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| Series: | Interdisciplinary Neurosurgery |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751917302761 |
| _version_ | 1819258928182067200 |
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| author | Michaël J. Bos, MD Linda Ackermans, MD, PhD Frédéric L.W.V.J. Schaper, MD Rob P.W. Rouhl, MD, PhD Vivianne H.J.M. van Kranen-Mastenbroek, MD, PhD Wolfgang F. Buhre, MD, PhD Marcus L.F. Janssen, MD, PhD |
| author_facet | Michaël J. Bos, MD Linda Ackermans, MD, PhD Frédéric L.W.V.J. Schaper, MD Rob P.W. Rouhl, MD, PhD Vivianne H.J.M. van Kranen-Mastenbroek, MD, PhD Wolfgang F. Buhre, MD, PhD Marcus L.F. Janssen, MD, PhD |
| author_sort | Michaël J. Bos, MD |
| collection | DOAJ |
| description | Deep brain stimulation of the anterior nucleus of the thalamus is an effective treatment for patients with refractory epilepsy who do not respond sufficiently to medical therapy. Optimal therapeutic effects of deep brain stimulation probably depend on accurate positioning of the stimulating electrodes. Microelectrode recordings show bursty firing neurons in the anterior nucleus of the thalamus region, which confirms the anatomical target determined by the surgeon. Deep brain stimulation electrodes in epilepsy patients are implanted under general anesthesia. The type and depth of anesthesia might interfere with microelectrode ecordings. Here, we describe our experience of a patient who underwent deep brain stimulation surgery under general anesthesia with sevoflurane, a volatile anesthetic, and its effect on the microelectrode recordings. Keywords: Thalamus, Deep brain stimulation, Sevoflurane |
| first_indexed | 2024-12-23T19:01:54Z |
| format | Article |
| id | doaj.art-c99a0bc54a3c453fb93e8537d7b941d5 |
| institution | Directory Open Access Journal |
| issn | 2214-7519 |
| language | English |
| last_indexed | 2024-12-23T19:01:54Z |
| publishDate | 2018-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj.art-c99a0bc54a3c453fb93e8537d7b941d52022-12-21T17:34:41ZengElsevierInterdisciplinary Neurosurgery2214-75192018-06-01125658Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case reportMichaël J. Bos, MD0Linda Ackermans, MD, PhD1Frédéric L.W.V.J. Schaper, MD2Rob P.W. Rouhl, MD, PhD3Vivianne H.J.M. van Kranen-Mastenbroek, MD, PhD4Wolfgang F. Buhre, MD, PhD5Marcus L.F. Janssen, MD, PhD6Department of Anesthesiology and Pain Medicine, Maastricht University Medical Center, Maastricht, The Netherlands; School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands.School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.; Department of Neurology, Maastricht University Medical Center, Maastricht, The NetherlandsSchool for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.; Department of Neurology, Maastricht University Medical Center, Maastricht, The Netherlands; Academic Center for Epileptology Kempenhaeghe/MUMC+, Heeze and Maastricht, The NetherlandsDepartment of Neurophysiology, Maastricht University Medical Center, Maastricht, The NetherlandsDepartment of Anesthesiology and Pain Medicine, Maastricht University Medical Center, Maastricht, The NetherlandsSchool for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.; Department of Neurology, Maastricht University Medical Center, Maastricht, The Netherlands; Department of Neurophysiology, Maastricht University Medical Center, Maastricht, The Netherlands; Corresponding author at: Department of Neurology, P. Debyelaan 25, Postbus 5800, 6202 AZ Maastricht, The Netherlands.Deep brain stimulation of the anterior nucleus of the thalamus is an effective treatment for patients with refractory epilepsy who do not respond sufficiently to medical therapy. Optimal therapeutic effects of deep brain stimulation probably depend on accurate positioning of the stimulating electrodes. Microelectrode recordings show bursty firing neurons in the anterior nucleus of the thalamus region, which confirms the anatomical target determined by the surgeon. Deep brain stimulation electrodes in epilepsy patients are implanted under general anesthesia. The type and depth of anesthesia might interfere with microelectrode ecordings. Here, we describe our experience of a patient who underwent deep brain stimulation surgery under general anesthesia with sevoflurane, a volatile anesthetic, and its effect on the microelectrode recordings. Keywords: Thalamus, Deep brain stimulation, Sevofluranehttp://www.sciencedirect.com/science/article/pii/S2214751917302761 |
| spellingShingle | Michaël J. Bos, MD Linda Ackermans, MD, PhD Frédéric L.W.V.J. Schaper, MD Rob P.W. Rouhl, MD, PhD Vivianne H.J.M. van Kranen-Mastenbroek, MD, PhD Wolfgang F. Buhre, MD, PhD Marcus L.F. Janssen, MD, PhD Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report Interdisciplinary Neurosurgery |
| title | Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report |
| title_full | Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report |
| title_fullStr | Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report |
| title_full_unstemmed | Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report |
| title_short | Effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy: A case report |
| title_sort | effect of sevoflurane on neuronal activity during deep brain stimulation surgery for epilepsy a case report |
| url | http://www.sciencedirect.com/science/article/pii/S2214751917302761 |
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