Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy

Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy

Abstract Targeted therapies, such as endocrine therapies (ET), can exert selective pressure on cancer cells and promote adaptations that confer treatment resistance. In this study, we show that ET resistance in breast cancer drives radiation resistance through reprogramming of DNA repair pathways. W...

Full description

Bibliographic Details
Main Authors: S. M. Nashir Udden, GuemHee Baek, Kamal Pandey, Chantal Vidal, Yulun Liu, Asal S. Rahimi, D. Nathan Kim, Chika R. Nwachukwu, Ram S. Mani, Prasanna G. Alluri
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00348-1

Similar Items

Similar Items