Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities
Abstract Background: Birthweight less than 2500 grams is the major indicators of neonatal and infant health. The studies on animals show that copper and zinc deficiency in pregnancy is associated with fetal growth and congenital abnormalities. Therefore, our study was conducted to evaluate the role...
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| Format: | Article |
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Arak Medical University
2015-07-01
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| Series: | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk |
| Subjects: | |
| Online Access: | http://amuj.arakmu.ac.ir/article-1-3392-en.pdf |
| _version_ | 1818542625570947072 |
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| author | Zahra Jelodari Nahid Masood Poor Mohammad Asad Poor Meysam Hazeri Baghdad Abad Seyyed Hosein Shahcheraghi |
| author_facet | Zahra Jelodari Nahid Masood Poor Mohammad Asad Poor Meysam Hazeri Baghdad Abad Seyyed Hosein Shahcheraghi |
| author_sort | Zahra Jelodari |
| collection | DOAJ |
| description | Abstract
Background: Birthweight less than 2500 grams is the major indicators of neonatal and infant health. The studies on animals show that copper and zinc deficiency in pregnancy is associated with fetal growth and congenital abnormalities. Therefore, our study was conducted to evaluate the role of these two elements on human embryos.
Materials and Methods: In this descriptive study, cord blood of all infants born in Nik-Nafs Maternity of Rafsanjan was Collected for 1 year. Then, serum was separated and saved. In total, 64 samples including 9 infants with congenital anomalies, 21 infants with a weight equal to or less than 2500 grams and 34 healthy infants were selected randomly as control group. The level of copper and zinc in cord boold was measured by the spectrophotometric method and data analysis was carried out by SPSS 17 Software and statistical methods involving Chi-square, T-test and analysis of variznce.
Results: No significant relation was shown between the levels of copper and zinc withbirth weight and congenital abnormalities. Also, there was not any significant correlation between these two teo elements and some pregnancy risk factors such as type of delivery, premature rupture of membrane, placental decolman, placental previa, preeclampsia, gravidity, height, head circumference and Apgar scores.
Conclusion: The findings indicate that the levels of copper and zinc in cord blood are not associated with incidence of low birth weight, congenital malformations and pregnancy risk factors. |
| first_indexed | 2024-12-11T22:24:34Z |
| format | Article |
| id | doaj.art-c9a0e863b06d42e79ab930599288c6b1 |
| institution | Directory Open Access Journal |
| issn | 1735-5338 2008-644X |
| language | fas |
| last_indexed | 2024-12-11T22:24:34Z |
| publishDate | 2015-07-01 |
| publisher | Arak Medical University |
| record_format | Article |
| series | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk |
| spelling | doaj.art-c9a0e863b06d42e79ab930599288c6b12022-12-22T00:48:20ZfasArak Medical UniversityMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk1735-53382008-644X2015-07-011841825Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital AbnormalitiesZahra Jelodari0Nahid Masood Poor1Mohammad Asad Poor2Meysam Hazeri Baghdad Abad3Seyyed Hosein Shahcheraghi4Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Department of Pediatrics, Rafsanjan University of Medics Sciences, Rafsanjan, Iran.Department of Social Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Tropical Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Abstract Background: Birthweight less than 2500 grams is the major indicators of neonatal and infant health. The studies on animals show that copper and zinc deficiency in pregnancy is associated with fetal growth and congenital abnormalities. Therefore, our study was conducted to evaluate the role of these two elements on human embryos. Materials and Methods: In this descriptive study, cord blood of all infants born in Nik-Nafs Maternity of Rafsanjan was Collected for 1 year. Then, serum was separated and saved. In total, 64 samples including 9 infants with congenital anomalies, 21 infants with a weight equal to or less than 2500 grams and 34 healthy infants were selected randomly as control group. The level of copper and zinc in cord boold was measured by the spectrophotometric method and data analysis was carried out by SPSS 17 Software and statistical methods involving Chi-square, T-test and analysis of variznce. Results: No significant relation was shown between the levels of copper and zinc withbirth weight and congenital abnormalities. Also, there was not any significant correlation between these two teo elements and some pregnancy risk factors such as type of delivery, premature rupture of membrane, placental decolman, placental previa, preeclampsia, gravidity, height, head circumference and Apgar scores. Conclusion: The findings indicate that the levels of copper and zinc in cord blood are not associated with incidence of low birth weight, congenital malformations and pregnancy risk factors.http://amuj.arakmu.ac.ir/article-1-3392-en.pdfCopperZincCongenital AbnormalitiesLow Birth Weight |
| spellingShingle | Zahra Jelodari Nahid Masood Poor Mohammad Asad Poor Meysam Hazeri Baghdad Abad Seyyed Hosein Shahcheraghi Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk Copper Zinc Congenital Abnormalities Low Birth Weight |
| title | Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities |
| title_full | Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities |
| title_fullStr | Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities |
| title_full_unstemmed | Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities |
| title_short | Comparison of Serum Level of Cord Blood Copper and Zinc and its Relationship with Infant’s Birth Weight and Congenital Abnormalities |
| title_sort | comparison of serum level of cord blood copper and zinc and its relationship with infant s birth weight and congenital abnormalities |
| topic | Copper Zinc Congenital Abnormalities Low Birth Weight |
| url | http://amuj.arakmu.ac.ir/article-1-3392-en.pdf |
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