Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

The joints of mammals are lined with cartilage, comprised of individual chondrocytes embedded in a specialized extracellular matrix. Chondrocytes experience a complex mechanical environment and respond to changing mechanical loads in order to maintain cartilage homeostasis. It has been proposed that...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: M Rocio Servin-Vences, Mirko Moroni, Gary R Lewin, Kate Poole
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: eLife Sciences Publications Ltd 2017-01-01
Cyfres:eLife
Pynciau:
Mynediad Ar-lein:https://elifesciences.org/articles/21074