Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

The joints of mammals are lined with cartilage, comprised of individual chondrocytes embedded in a specialized extracellular matrix. Chondrocytes experience a complex mechanical environment and respond to changing mechanical loads in order to maintain cartilage homeostasis. It has been proposed that...

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Detalhes bibliográficos
Principais autores: M Rocio Servin-Vences, Mirko Moroni, Gary R Lewin, Kate Poole
Formato: Artigo
Idioma:English
Publicado em: eLife Sciences Publications Ltd 2017-01-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/21074