Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes
The joints of mammals are lined with cartilage, comprised of individual chondrocytes embedded in a specialized extracellular matrix. Chondrocytes experience a complex mechanical environment and respond to changing mechanical loads in order to maintain cartilage homeostasis. It has been proposed that...
Principais autores: | , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
eLife Sciences Publications Ltd
2017-01-01
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coleção: | eLife |
Assuntos: | |
Acesso em linha: | https://elifesciences.org/articles/21074 |