Endobronchial blood-patch: A novel technique for a persistent pleural air leak

Introduction: Patients with severe COVID-19 Pneumonia requiring prolonged mechanical ventilation have an increased incidence of pneumothorax. Mechanically ventilated patients who are critically ill and develop a persistent air leak from pneumothorax are poor candidates for surgical repair. As the pe...

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Main Authors: Richard J. Durrance, Kenneth G. D'Souza, Reiichiro Obata, Ellen C. Bradley, Muhammad K. Perwaiz
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007122000922
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author Richard J. Durrance
Kenneth G. D'Souza
Reiichiro Obata
Ellen C. Bradley
Muhammad K. Perwaiz
author_facet Richard J. Durrance
Kenneth G. D'Souza
Reiichiro Obata
Ellen C. Bradley
Muhammad K. Perwaiz
author_sort Richard J. Durrance
collection DOAJ
description Introduction: Patients with severe COVID-19 Pneumonia requiring prolonged mechanical ventilation have an increased incidence of pneumothorax. Mechanically ventilated patients who are critically ill and develop a persistent air leak from pneumothorax are poor candidates for surgical repair. As the persistent air leak can be a significant barrier to vent-weaning and clinical stability, these patients present a unique clinical challenge. Clinical case: A 65-year-old male intubated and on prolonged mechanical ventilation for severe COVID-19 Pneumonia developed a pneumothorax complicated by a persistent alveolar-pleural fistula with a persistent air-leak. Given his critical state with ongoing pressor requirements and elevated vent requirements, surgical repair was not an option. A bedside bronchoscopy occlusion study with isolation of the air leak, and subsequent autologous endobronchial blood-patch repair with thrombin was performed with rapid and definitive resolution of the air leak. The patient progressed favorably, ultimately being weaned from the ventilator, decannulated, and walking out of the hospital. Conclusion: In critically ill ventilated patients with pneumothorax complicated by a persistent air-leak, bedside endobronchial evaluation and blood-patch repair is a feasible approach to management.
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spelling doaj.art-c9b068ea87da46c1ab296f1b963594732022-12-22T00:54:14ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0138101670Endobronchial blood-patch: A novel technique for a persistent pleural air leakRichard J. Durrance0Kenneth G. D'Souza1Reiichiro Obata2Ellen C. Bradley3Muhammad K. Perwaiz4Pulmonary-Critical Care Fellow. Icahn School of Medicine at Mount Sinai, Elmhurst Hospital, United States; Corresponding author.Pulmonary-Critical Care Fellow. Icahn School of Medicine at Mount Sinai, Elmhurst Hospital, United StatesPulmonary-Critical Care Fellow. Icahn School of Medicine at Mount Sinai, Elmhurst Hospital, United StatesPulmonary-Critical Care Fellow. Icahn School of Medicine at Mount Sinai, Elmhurst Hospital, United StatesInterventional Pulmonology and Pulmonary Critical Care Attending, Icahn School of Medicine at Mount Sinai: Elmhurst Hospital, United StatesIntroduction: Patients with severe COVID-19 Pneumonia requiring prolonged mechanical ventilation have an increased incidence of pneumothorax. Mechanically ventilated patients who are critically ill and develop a persistent air leak from pneumothorax are poor candidates for surgical repair. As the persistent air leak can be a significant barrier to vent-weaning and clinical stability, these patients present a unique clinical challenge. Clinical case: A 65-year-old male intubated and on prolonged mechanical ventilation for severe COVID-19 Pneumonia developed a pneumothorax complicated by a persistent alveolar-pleural fistula with a persistent air-leak. Given his critical state with ongoing pressor requirements and elevated vent requirements, surgical repair was not an option. A bedside bronchoscopy occlusion study with isolation of the air leak, and subsequent autologous endobronchial blood-patch repair with thrombin was performed with rapid and definitive resolution of the air leak. The patient progressed favorably, ultimately being weaned from the ventilator, decannulated, and walking out of the hospital. Conclusion: In critically ill ventilated patients with pneumothorax complicated by a persistent air-leak, bedside endobronchial evaluation and blood-patch repair is a feasible approach to management.http://www.sciencedirect.com/science/article/pii/S2213007122000922Alveolar-pleural fistulaPersistent air leakCovid-19Bronchoscopic air-leak repair
spellingShingle Richard J. Durrance
Kenneth G. D'Souza
Reiichiro Obata
Ellen C. Bradley
Muhammad K. Perwaiz
Endobronchial blood-patch: A novel technique for a persistent pleural air leak
Respiratory Medicine Case Reports
Alveolar-pleural fistula
Persistent air leak
Covid-19
Bronchoscopic air-leak repair
title Endobronchial blood-patch: A novel technique for a persistent pleural air leak
title_full Endobronchial blood-patch: A novel technique for a persistent pleural air leak
title_fullStr Endobronchial blood-patch: A novel technique for a persistent pleural air leak
title_full_unstemmed Endobronchial blood-patch: A novel technique for a persistent pleural air leak
title_short Endobronchial blood-patch: A novel technique for a persistent pleural air leak
title_sort endobronchial blood patch a novel technique for a persistent pleural air leak
topic Alveolar-pleural fistula
Persistent air leak
Covid-19
Bronchoscopic air-leak repair
url http://www.sciencedirect.com/science/article/pii/S2213007122000922
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AT reiichiroobata endobronchialbloodpatchanoveltechniqueforapersistentpleuralairleak
AT ellencbradley endobronchialbloodpatchanoveltechniqueforapersistentpleuralairleak
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