Regulation of TERRA on telomeric and mitochondrial functions in IPF pathogenesis

Regulation of TERRA on telomeric and mitochondrial functions in IPF pathogenesis

Abstract Background Aging is a known risk factor of idiopathic pulmonary fibrosis (IPF). However, the pathogenic mechanisms underlying the effects of advanced aging remain largely unknown. Telomeric repeat-containing RNA (TERRA) represents a type of long noncoding RNA. In this study, the regulatory...

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Bibliographic Details
Main Authors: Yulin Gao, Jinjin Zhang, Yuxia Liu, Songzi Zhang, Youlei Wang, Bo Liu, Huizhu Liu, Rongrong Li, Changjun Lv, Xiaodong Song
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Pulmonary Medicine
Subjects:
IPF
lncRNA
Telomere
Mitochondria
TERRA
Online Access:http://link.springer.com/article/10.1186/s12890-017-0516-1

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