Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

In light of the current outbreak of Ebola virus disease, there is an urgent need to develop effective therapeutics to treat Ebola infection, and drug repurposing screening is a potentially rapid approach for identifying such therapeutics. We developed a biosafety level 2 (BSL-2) 1536-well plate assa...

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Bibliographic Details
Main Authors: Jennifer Kouznetsova, Wei Sun, Carles Martínez-Romero, Gregory Tawa, Paul Shinn, Catherine Z Chen, Aaron Schimmer, Philip Sanderson, John C McKew, Wei Zheng, Adolfo García-Sastre
Format: Article
Language:English
Published: Taylor & Francis Group 2014-01-01
Series:Emerging Microbes and Infections
Subjects:
Antipsychotics
drug repurposing screen
Ebola virus
Ebola virus glycoprotein
estrogen receptor modulator
microtubule inhibitor
Online Access:https://www.tandfonline.com/doi/10.1038/emi.2014.88

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