Embedded Human Periodontal Ligament Stem Cells Spheroids Enhance Cementogenic Differentiation via Plasminogen Activator Inhibitor 1

Embedded Human Periodontal Ligament Stem Cells Spheroids Enhance Cementogenic Differentiation via Plasminogen Activator Inhibitor 1

Spheroids reproduce the tissue structure that is found in vivo more accurately than classic two-dimensional (2D) monolayer cultures. We cultured human periodontal ligament stem cells (HPLSCs) as spheroids that were embedded in collagen gel to examine whether their cementogenic differentiation could...

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Bibliographic Details
Main Authors:	Madoka Yasunaga, Hiroyuki Ishikawa, Sachio Tamaoki, Hidefumi Maeda, Jun Ohno
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	International Journal of Molecular Sciences
Subjects:	human periodontal ligament stem cells spheroids collagen embedding culture plasminogen activator inhibitor 1 cementogenic differentiation cementum protein 1
Online Access:	https://www.mdpi.com/1422-0067/23/4/2340

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