A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia
Eighty male patients with AGA, not treated in the previous 6 months were enrolled in this randomized, double blind, placebo controlled trial to assess the safety and efficacy of finasteride, 1mg daily, on hair growth. Patients were randomized into 2 groups: Group 1 received 1 mg of finasteride daily...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2005-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2005;volume=50;issue=3;spage=139;epage=145;aulast=Prasad |
| _version_ | 1819182490703626240 |
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| author | Prasad H Khanna Neena Pandhi R |
| author_facet | Prasad H Khanna Neena Pandhi R |
| author_sort | Prasad H |
| collection | DOAJ |
| description | Eighty male patients with AGA, not treated in the previous 6 months were enrolled in this randomized, double blind, placebo controlled trial to assess the safety and efficacy of finasteride, 1mg daily, on hair growth. Patients were randomized into 2 groups: Group 1 received 1 mg of finasteride daily and Group 2 received a placebo for a period of 12 months. Efficacy was assessed by hair counts, photographic records, patient′s self-assessment questionnaire and clinical assessment. Safety was assessed by history taking and laboratory parameters. A total of 39 patients completed the study. Finasteride was rated superior to placebo with respect to all efficacy measures. At the end of study, finasteride treated patients had a mean increase of 20.56±4.73 hairs compared to a decrease of 9.56±5.53 hairs in placebo treated patients. Photographically, 69.56% of finasteride treated patients were rated as improved at 12 months compared to only 6.25% of placebo treated patients. Ten (25%) of finasteride treated patients developed adverse effects (5-decreased libido as well as erectile dysfunction, 4-erectile dysfunction, 1-decreased libido). Finasteride in comparison to placebo was effective in promoting hair growth in male patients of AGA. However, the side effects to the drug were high in this study. |
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| format | Article |
| id | doaj.art-c9b62c4d8fce4220b2437cee9c7c6da7 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 |
| language | English |
| last_indexed | 2024-12-22T22:46:58Z |
| publishDate | 2005-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-c9b62c4d8fce4220b2437cee9c7c6da72022-12-21T18:10:03ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51542005-01-01503139145A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopeciaPrasad HKhanna NeenaPandhi REighty male patients with AGA, not treated in the previous 6 months were enrolled in this randomized, double blind, placebo controlled trial to assess the safety and efficacy of finasteride, 1mg daily, on hair growth. Patients were randomized into 2 groups: Group 1 received 1 mg of finasteride daily and Group 2 received a placebo for a period of 12 months. Efficacy was assessed by hair counts, photographic records, patient′s self-assessment questionnaire and clinical assessment. Safety was assessed by history taking and laboratory parameters. A total of 39 patients completed the study. Finasteride was rated superior to placebo with respect to all efficacy measures. At the end of study, finasteride treated patients had a mean increase of 20.56±4.73 hairs compared to a decrease of 9.56±5.53 hairs in placebo treated patients. Photographically, 69.56% of finasteride treated patients were rated as improved at 12 months compared to only 6.25% of placebo treated patients. Ten (25%) of finasteride treated patients developed adverse effects (5-decreased libido as well as erectile dysfunction, 4-erectile dysfunction, 1-decreased libido). Finasteride in comparison to placebo was effective in promoting hair growth in male patients of AGA. However, the side effects to the drug were high in this study.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2005;volume=50;issue=3;spage=139;epage=145;aulast=PrasadFinasteride5-a reductase inhibitora0 ndrogenetic alopeciah0 air growth |
| spellingShingle | Prasad H Khanna Neena Pandhi R A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia Indian Journal of Dermatology Finasteride 5-a reductase inhibitor a0 ndrogenetic alopecia h0 air growth |
| title | A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia |
| title_full | A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia |
| title_fullStr | A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia |
| title_full_unstemmed | A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia |
| title_short | A randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia |
| title_sort | randomized double blind study of the effect of finasteride on hair growth in male patients of androgenetic alopecia |
| topic | Finasteride 5-a reductase inhibitor a0 ndrogenetic alopecia h0 air growth |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2005;volume=50;issue=3;spage=139;epage=145;aulast=Prasad |
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