Application of metal-based biomaterials in wound repair
Wound repair, as one of the most intricate biological mechanisms, is essential to ensure the formation and integrity of the skin barrier. However, multiple factors can cause delays and severe debilitating effects in wound repair, which bring serious challenges. Metal elements such as calcium, copper...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2021-01-01
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| Series: | Engineered Regeneration |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266613812100013X |
| _version_ | 1818824363347017728 |
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| author | Heni Wang Zejun Xu Qing Li Jun Wu |
| author_facet | Heni Wang Zejun Xu Qing Li Jun Wu |
| author_sort | Heni Wang |
| collection | DOAJ |
| description | Wound repair, as one of the most intricate biological mechanisms, is essential to ensure the formation and integrity of the skin barrier. However, multiple factors can cause delays and severe debilitating effects in wound repair, which bring serious challenges. Metal elements such as calcium, copper, iron, and zinc serve irreplaceable roles in various regulatory pathways of the human body and directly or indirectly affect the orderly wound repair process. Biomaterials have proven to be an attractive strategy that can be applied to wound repair and have excellent potential to induce skin regeneration. In recent decades, with in-depth research on the regulatory mechanisms of metal elements involved in wound repair, metal-based biomaterials have been widely reported. Metal-based zero-dimensional (0D) biomaterials such as Ångstrom-scale metallic materials and metal quantum dots, metal-based one-dimensional (1D) biomaterials such as nanorods, nanowires and nanofibers, metal-based two-dimensional (2D) biomaterials such as nanofilms and nanosheets, and metal-based three-dimensional (3D) biomaterials such as nanoframes have achieved remarkable results, which provide great support for accelerated wound repair. In this review, we systematically investigated the advances and impacts of various metal-based biomaterial platforms for wound repair to provide valuable guidance for future breakthroughs in wound treatment. |
| first_indexed | 2024-12-18T23:54:41Z |
| format | Article |
| id | doaj.art-c9b66cfcfd5441e1821fb74814c155f5 |
| institution | Directory Open Access Journal |
| issn | 2666-1381 |
| language | English |
| last_indexed | 2024-12-18T23:54:41Z |
| publishDate | 2021-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Engineered Regeneration |
| spelling | doaj.art-c9b66cfcfd5441e1821fb74814c155f52022-12-21T20:46:46ZengKeAi Communications Co., Ltd.Engineered Regeneration2666-13812021-01-012137153Application of metal-based biomaterials in wound repairHeni Wang0Zejun Xu1Qing Li2Jun Wu3School of Biomedical Engineering, Sun Yat-sen University, Shenzhen 518107, PR ChinaSchool of Biomedical Engineering, Sun Yat-sen University, Shenzhen 518107, PR ChinaSchool and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinnan, Shandong, ChinaCorresponding author.; School of Biomedical Engineering, Sun Yat-sen University, Shenzhen 518107, PR ChinaWound repair, as one of the most intricate biological mechanisms, is essential to ensure the formation and integrity of the skin barrier. However, multiple factors can cause delays and severe debilitating effects in wound repair, which bring serious challenges. Metal elements such as calcium, copper, iron, and zinc serve irreplaceable roles in various regulatory pathways of the human body and directly or indirectly affect the orderly wound repair process. Biomaterials have proven to be an attractive strategy that can be applied to wound repair and have excellent potential to induce skin regeneration. In recent decades, with in-depth research on the regulatory mechanisms of metal elements involved in wound repair, metal-based biomaterials have been widely reported. Metal-based zero-dimensional (0D) biomaterials such as Ångstrom-scale metallic materials and metal quantum dots, metal-based one-dimensional (1D) biomaterials such as nanorods, nanowires and nanofibers, metal-based two-dimensional (2D) biomaterials such as nanofilms and nanosheets, and metal-based three-dimensional (3D) biomaterials such as nanoframes have achieved remarkable results, which provide great support for accelerated wound repair. In this review, we systematically investigated the advances and impacts of various metal-based biomaterial platforms for wound repair to provide valuable guidance for future breakthroughs in wound treatment.http://www.sciencedirect.com/science/article/pii/S266613812100013XWound repairMetalBiomaterials |
| spellingShingle | Heni Wang Zejun Xu Qing Li Jun Wu Application of metal-based biomaterials in wound repair Engineered Regeneration Wound repair Metal Biomaterials |
| title | Application of metal-based biomaterials in wound repair |
| title_full | Application of metal-based biomaterials in wound repair |
| title_fullStr | Application of metal-based biomaterials in wound repair |
| title_full_unstemmed | Application of metal-based biomaterials in wound repair |
| title_short | Application of metal-based biomaterials in wound repair |
| title_sort | application of metal based biomaterials in wound repair |
| topic | Wound repair Metal Biomaterials |
| url | http://www.sciencedirect.com/science/article/pii/S266613812100013X |
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