Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete
Purpose: The aim of the current study is to disseminate long-term “real-world” data on mortality and device therapies in primary and secondary prevention implantable cardioverter defibrillator (ICD) recipients on the island of Crete. Methods: We analyzed data for all consecutive patients who receive...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-07-01
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| Series: | Hellenic Journal of Cardiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1109966616301476 |
| _version_ | 1818020721261019136 |
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| author | Emmanuel M. Kanoupakis John A. Fanourgiakis Hercules E. Mavrakis Eleutherios M. Kallergis Emmanuel N. Simantirakis Stavros I. Crysostomakis Ilias G. Saloustros Gregory I. Chlouverakis Panos E. Vardas |
| author_facet | Emmanuel M. Kanoupakis John A. Fanourgiakis Hercules E. Mavrakis Eleutherios M. Kallergis Emmanuel N. Simantirakis Stavros I. Crysostomakis Ilias G. Saloustros Gregory I. Chlouverakis Panos E. Vardas |
| author_sort | Emmanuel M. Kanoupakis |
| collection | DOAJ |
| description | Purpose: The aim of the current study is to disseminate long-term “real-world” data on mortality and device therapies in primary and secondary prevention implantable cardioverter defibrillator (ICD) recipients on the island of Crete.
Methods: We analyzed data for all consecutive patients who received an ICD in our tertiary university hospital from 1993 until December 2013. Follow-up visits were performed every 6 months or more frequently when indicated. Survival status was recorded, and all stored episodes during interrogation were registered and classified as appropriate or inappropriate.
Results: In total, 854 patients received an ICD; 623 (73%) for primary and 231 (27%) for secondary prevention. Most of these patients (490) suffered from ischemic cardiomyopathy. During the mean follow-up of 12.4 ± 7.8 years, 218 (25.5%) patients died; 19.7% in the primary prevention group (p=0.008) and 41.1% in the secondary prevention group. Overall, 248 patients (29%) received appropriate therapy; however, the percentage was significantly higher in the secondary prevention group (44.2%) than in primary prevention group (23.4%). The cumulative incidence of inappropriate therapies during the mean follow-up period was 11.6%. Lead-related complications were noted in 49 patients (5.7%), while only 13 patients (1.5%) suffered device-related infections.
Conclusions: The long-term data related to clinical outcomes in ICD recipients in our center are in accordance with those of other international centers and confirm the high efficacy and safety of these devices in preventing sudden cardiac death. |
| first_indexed | 2024-04-14T08:09:17Z |
| format | Article |
| id | doaj.art-c9bcb586a7d84582b30a0b9f2bb0832a |
| institution | Directory Open Access Journal |
| issn | 1109-9666 |
| language | English |
| last_indexed | 2024-04-14T08:09:17Z |
| publishDate | 2016-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hellenic Journal of Cardiology |
| spelling | doaj.art-c9bcb586a7d84582b30a0b9f2bb0832a2022-12-22T02:04:38ZengElsevierHellenic Journal of Cardiology1109-96662016-07-0157424725210.1016/j.hjc.2016.05.004Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of CreteEmmanuel M. Kanoupakis0John A. Fanourgiakis1Hercules E. Mavrakis2Eleutherios M. Kallergis3Emmanuel N. Simantirakis4Stavros I. Crysostomakis5Ilias G. Saloustros6Gregory I. Chlouverakis7Panos E. Vardas8Cardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreeceDepartment of Biostatistics, Faculty of Medicine, University of Crete, GreeceCardiology Department, University Hospital of Heraklion, Heraklion, Crete, GreecePurpose: The aim of the current study is to disseminate long-term “real-world” data on mortality and device therapies in primary and secondary prevention implantable cardioverter defibrillator (ICD) recipients on the island of Crete. Methods: We analyzed data for all consecutive patients who received an ICD in our tertiary university hospital from 1993 until December 2013. Follow-up visits were performed every 6 months or more frequently when indicated. Survival status was recorded, and all stored episodes during interrogation were registered and classified as appropriate or inappropriate. Results: In total, 854 patients received an ICD; 623 (73%) for primary and 231 (27%) for secondary prevention. Most of these patients (490) suffered from ischemic cardiomyopathy. During the mean follow-up of 12.4 ± 7.8 years, 218 (25.5%) patients died; 19.7% in the primary prevention group (p=0.008) and 41.1% in the secondary prevention group. Overall, 248 patients (29%) received appropriate therapy; however, the percentage was significantly higher in the secondary prevention group (44.2%) than in primary prevention group (23.4%). The cumulative incidence of inappropriate therapies during the mean follow-up period was 11.6%. Lead-related complications were noted in 49 patients (5.7%), while only 13 patients (1.5%) suffered device-related infections. Conclusions: The long-term data related to clinical outcomes in ICD recipients in our center are in accordance with those of other international centers and confirm the high efficacy and safety of these devices in preventing sudden cardiac death.http://www.sciencedirect.com/science/article/pii/S1109966616301476Implantable cardioverter defibrillatorMortalityAppropriate therapyComplications |
| spellingShingle | Emmanuel M. Kanoupakis John A. Fanourgiakis Hercules E. Mavrakis Eleutherios M. Kallergis Emmanuel N. Simantirakis Stavros I. Crysostomakis Ilias G. Saloustros Gregory I. Chlouverakis Panos E. Vardas Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete Hellenic Journal of Cardiology Implantable cardioverter defibrillator Mortality Appropriate therapy Complications |
| title | Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete |
| title_full | Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete |
| title_fullStr | Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete |
| title_full_unstemmed | Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete |
| title_short | Long-term clinical outcomes in implantable cardioverter defibrillator recipients on the island of Crete |
| title_sort | long term clinical outcomes in implantable cardioverter defibrillator recipients on the island of crete |
| topic | Implantable cardioverter defibrillator Mortality Appropriate therapy Complications |
| url | http://www.sciencedirect.com/science/article/pii/S1109966616301476 |
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