Micro-PET/CT Monitoring of Herpes Thymidine Kinase Suicide Gene Therapy in a Prostate Cancer Xenograft: The Advantage of a Cell-specific Transcriptional Targeting Approach

Micro-PET/CT Monitoring of Herpes Thymidine Kinase Suicide Gene Therapy in a Prostate Cancer Xenograft: The Advantage of a Cell-specific Transcriptional Targeting Approach

Cancer gene therapy based on tissue-restricted expression of cytotoxic gene should achieve superior therapeutic index over an unrestricted method. This study compared the therapeutic effects of a highly augmented, prostate-specific gene expression method to a strong constitutive promoter-driven appr...

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Bibliographic Details
Main Authors: Mai Johnson, Makoto Sato, Jeremy Burton, Sanjiv S. Gambhir, Michael Carey, Lily Wu
Format: Article
Language:English
Published: SAGE Publishing 2005-10-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2005.05154

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