High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study.
Background: During the COVID-19 pandemic, the pattern of medical services changed to minimize transmission to health care workers (HCWs) or hospitalized patients. Despite the care of COVID-19 patients in a special ward, new cases are accidentally discovered. This study aimed at determining the antib...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zagazig University, Faculty of Medicine
2022-10-01
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| Series: | Microbes and Infectious Diseases |
| Subjects: | |
| Online Access: | https://mid.journals.ekb.eg/article_258242_4724633e33a8788da490a366c1b7e4d1.pdf |
| _version_ | 1797989264381706240 |
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| author | Bassam Mansour adel hassan Fadia Attia Safaa Mohamed Mohamed Abdo Eman Fahmy Samar Mohamed AG Abdel Rahman Bassma Ibrahem Wagdy Abdelfatah Moustafa Ragheb |
| author_facet | Bassam Mansour adel hassan Fadia Attia Safaa Mohamed Mohamed Abdo Eman Fahmy Samar Mohamed AG Abdel Rahman Bassma Ibrahem Wagdy Abdelfatah Moustafa Ragheb |
| author_sort | Bassam Mansour |
| collection | DOAJ |
| description | Background: During the COVID-19 pandemic, the pattern of medical services changed to minimize transmission to health care workers (HCWs) or hospitalized patients. Despite the care of COVID-19 patients in a special ward, new cases are accidentally discovered. This study aimed at determining the antibody seroprevalence among asymptomatic HCWs and the associated risks. Methods: The study involved 190 participants, including physicians, nurses, technicians, and administrative staff. All were inquired for sociodemographic, specialty, previous isolation, and previous infection, and their blood was tested for SARS-CoV2 antibody. Results: Of 190 HCWs; 72,1% were females, the mean age was 32.6±7.9 years, 10.5% were smokers, and 15.8% reported co-morbid illness. SARS CoV2 antibodies were found in 68 (35.8%); being IgG, IgM and both IgM and IgG in 47 (69.1%), 10 (14.7%) and 11 (16.2%) participants respectively. The prevalence was higher (47.6%) among HCWs of the COVID unit, [OR=1.7 (95% CI: 0.69-4.3)] and HCWs with previous COVID-19, OR:1.61 (95% CI:0.88-2.94). The prevalence was significantly lower among smokers (p=0.049), OR:0.29 (95% CI:0.08-1.01), and significantly higher in HCWs who recalled cough (p=0.036) OR: 1.97 (95% CI: 1.05-3.69). The likelihood of antibody seropositivity increased in technicians [OR:2.02 (95% CI: 0.92-4.44)], followed by physicians [OR:1.7 (95% CI: 0.7-4.33)] while the odds ratio was low among nurses [OR:0.58 (95% CI: 0.32-1.07). Conclusion: A considerable proportion of antibody positive HCWs had evidence of past SARS CoV2. Provision of adequate personal protective equipment and periodic screening of HCWs are urgently needed to lessen the transmission within the health care settings. |
| first_indexed | 2024-04-11T08:17:15Z |
| format | Article |
| id | doaj.art-c9bf190aa390409e9682c6ad032efc4f |
| institution | Directory Open Access Journal |
| issn | 2682-4132 2682-4140 |
| language | English |
| last_indexed | 2024-04-11T08:17:15Z |
| publishDate | 2022-10-01 |
| publisher | Zagazig University, Faculty of Medicine |
| record_format | Article |
| series | Microbes and Infectious Diseases |
| spelling | doaj.art-c9bf190aa390409e9682c6ad032efc4f2022-12-22T04:35:06ZengZagazig University, Faculty of MedicineMicrobes and Infectious Diseases2682-41322682-41402022-10-013484285110.21608/mid.2022.148952.1341258242High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study.Bassam Mansour0adel hassan1Fadia Attia2Safaa Mohamed3Mohamed Abdo4Eman Fahmy5Samar Mohamed6AG Abdel Rahman7Bassma Ibrahem8Wagdy Abdelfatah9Moustafa Ragheb10Infectious and endemic diseases, department, faculty of medicine, Suez canal university, Ismailia, EgyptInfectious and endemic diseases, department, faculty of medicine, Suez canal university ,Ismailia, EgyptClinical pathology department, faculty of medicine, Suez canal university, Ismailia, EgyptClinical pathology department, faculty of medicine, Suez canal university, Ismailia, EgyptInternal medicine department, faculty of medicine, Suez canal university, Ismailia, EgyptInternal medicine department, faculty of medicine, Suez canal university, Ismailia, EgyptFamily Medicine Department, Faculty of Medicine, Suez Canal University, Ismailia, EgyptDepartment of Public health, Community Medicine, Environmental Medicine and Occupational Medicine, Faculty of Medicine, Suez Canal University, Ismailia, EgyptDepartment of Public health, Community Medicine, Environmental Medicine and Occupational Medicine, Faculty of Medicine, Suez Canal University, Ismailia, EgyptDepartment of chest diseases, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.Infectious and endemic diseases, department, faculty of medicine, Suez canal university, Ismailia, EgyptBackground: During the COVID-19 pandemic, the pattern of medical services changed to minimize transmission to health care workers (HCWs) or hospitalized patients. Despite the care of COVID-19 patients in a special ward, new cases are accidentally discovered. This study aimed at determining the antibody seroprevalence among asymptomatic HCWs and the associated risks. Methods: The study involved 190 participants, including physicians, nurses, technicians, and administrative staff. All were inquired for sociodemographic, specialty, previous isolation, and previous infection, and their blood was tested for SARS-CoV2 antibody. Results: Of 190 HCWs; 72,1% were females, the mean age was 32.6±7.9 years, 10.5% were smokers, and 15.8% reported co-morbid illness. SARS CoV2 antibodies were found in 68 (35.8%); being IgG, IgM and both IgM and IgG in 47 (69.1%), 10 (14.7%) and 11 (16.2%) participants respectively. The prevalence was higher (47.6%) among HCWs of the COVID unit, [OR=1.7 (95% CI: 0.69-4.3)] and HCWs with previous COVID-19, OR:1.61 (95% CI:0.88-2.94). The prevalence was significantly lower among smokers (p=0.049), OR:0.29 (95% CI:0.08-1.01), and significantly higher in HCWs who recalled cough (p=0.036) OR: 1.97 (95% CI: 1.05-3.69). The likelihood of antibody seropositivity increased in technicians [OR:2.02 (95% CI: 0.92-4.44)], followed by physicians [OR:1.7 (95% CI: 0.7-4.33)] while the odds ratio was low among nurses [OR:0.58 (95% CI: 0.32-1.07). Conclusion: A considerable proportion of antibody positive HCWs had evidence of past SARS CoV2. Provision of adequate personal protective equipment and periodic screening of HCWs are urgently needed to lessen the transmission within the health care settings.https://mid.journals.ekb.eg/article_258242_4724633e33a8788da490a366c1b7e4d1.pdfcovid-19hcwsegyptasymptomatic |
| spellingShingle | Bassam Mansour adel hassan Fadia Attia Safaa Mohamed Mohamed Abdo Eman Fahmy Samar Mohamed AG Abdel Rahman Bassma Ibrahem Wagdy Abdelfatah Moustafa Ragheb High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study. Microbes and Infectious Diseases covid-19 hcws egypt asymptomatic |
| title | High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study. |
| title_full | High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study. |
| title_fullStr | High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study. |
| title_full_unstemmed | High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study. |
| title_short | High SARS CoV2 antibody-prevalence among health care workers with variable exposure to COVID-19 patients: A cross-sectional university hospital study. |
| title_sort | high sars cov2 antibody prevalence among health care workers with variable exposure to covid 19 patients a cross sectional university hospital study |
| topic | covid-19 hcws egypt asymptomatic |
| url | https://mid.journals.ekb.eg/article_258242_4724633e33a8788da490a366c1b7e4d1.pdf |
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