The Association Between Tobacco Use and Risk of COVID-19 Infection and Clinical Outcomes in Sweden: A Population-Based Study

Background: The association between tobacco use and COVID-19 is controversial. During the early course of the pandemic, limited testing prevented studying a wide spectrum of clinical manifestations.Objective: To examine the potential causal association between tobacco use and COVID-19 during the sec...

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Bibliographic Details
Main Authors: A. N. Shaaban, F. Andersson, S. Peña, I. H. Caspersen, C. Magnusson, N. Orsini, S. Karvonen, P. Magnus, M. P. Hergens, M. R. Galanti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:International Journal of Public Health
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Online Access:https://www.ssph-journal.org/articles/10.3389/ijph.2023.1606175/full
Description
Summary:Background: The association between tobacco use and COVID-19 is controversial. During the early course of the pandemic, limited testing prevented studying a wide spectrum of clinical manifestations.Objective: To examine the potential causal association between tobacco use and COVID-19 during the second wave (1 October 2020–30 June 2021) of the pandemic in Stockholm, Sweden.Methods: A population-based cohort study was conducted in the Stockholm region of Sweden, with information on tobacco use collected prior to the pandemic. Adjusted relative risks (RR) of COVID-19 and 95% confidence intervals (CI) were calculated, contrasting current smokers and snus users to non-users of tobacco.Results: Compared with non-users of tobacco, current smokers had a lower risk of COVID-19 (RR 0.78, 95% CI = 0.75–0.81) and of hospitalisation for the disease. Current snus users had a higher risk of COVID-19. Heavy smokers and snus users had longer hospital stays than non-users of tobacco.Conclusion: Tobacco use may have a different impact on the risk of being infected with SARS-CoV-2 and the risk of developing severe clinical manifestations. Further research is needed to determine the underlying mechanisms.
ISSN:1661-8564