Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection
Introduction:Roasted and spicy food (mainly hot pepper) consumption is very common in Southeastern Anatolia. Smoked and spicy diets and Helicobacter pylori (H. pylori) infection are known risk factors for gastric cancer. The aim of this study was to investigate the effects of eating habits on the ga...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-02-01
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| Series: | İstanbul Medical Journal |
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http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/common-findings-in-endoscopic-gastric-biopsies-in-/43922
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| _version_ | 1797916110162493440 |
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| author | Burçin Pehlivanoğlu Bilge Aydın Türk Serap İşler Zülfükar Bilge |
| author_facet | Burçin Pehlivanoğlu Bilge Aydın Türk Serap İşler Zülfükar Bilge |
| author_sort | Burçin Pehlivanoğlu |
| collection | DOAJ |
| description | Introduction:Roasted and spicy food (mainly hot pepper) consumption is very common in Southeastern Anatolia. Smoked and spicy diets and Helicobacter pylori (H. pylori) infection are known risk factors for gastric cancer. The aim of this study was to investigate the effects of eating habits on the gastric mucosa, to investigate the rate of H. pylori positivity, and to examine the association of these factors with histopathological features in this region.Methods:Histopathological findings in endoscopic biopsies of 943 consecutive patients were retrospectively evaluated.Results:More than half of the patients were female (54%; n=505), and the median age was 47±17.27 (range: 18-96). The most common non-gastritis histopathologic diagnosis was gastric carcinoma (2.5%; n=24), followed by polypoid lesions (1.6%; n=16). The vast majority of patients (92%) had chronic gastritis, and neutrophilic activity was present in 61% (n=537). The frequencies of atrophy, intestinal metaplasia, and regenerative mucosal changes were significantly correlated with the severity of neutrophilic activity (p<0.05). Patients with atrophy and intestinal metaplasia were significantly older than those without atrophy and intestinal metaplasia (p<0.001; mean age: 47 and 46 vs 56 and 55, respectively). More than 50% were infected with H. pylori (57%; n=542), and H. pylori positivity was associated with the presence of chronic and chronic active gastritis, as well as lymphoid hyperplasia (p<0.001). In contrast, erosion, atrophy, and neuroendocrine cell hyperplasia were less common in patients with H. pylori gastritis (p<0.05).Conclusion:H. pylori infection and spicy food consumption are key risk factors for gastritis in Southeastern Anatolia. Prospective epidemiological studies are needed to better demonstrate the causal interaction between dietary factors and gastritis. |
| first_indexed | 2024-04-10T12:52:02Z |
| format | Article |
| id | doaj.art-c9c6d0f1da084372a6d4ac509d07ec5b |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T12:52:02Z |
| publishDate | 2021-02-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-c9c6d0f1da084372a6d4ac509d07ec5b2023-02-15T16:13:43ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2021-02-01221505410.4274/imj.galenos.2020.7405013049054Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> InfectionBurçin Pehlivanoğlu0Bilge Aydın Türk1Serap İşler2Zülfükar Bilge3 Adıyaman Training and Research Hospital, Clinic of Pathology, Adıyaman, Turkey Adıyaman Training and Research Hospital, Clinic of Pathology, Adıyaman, Turkey Adıyaman Training and Research Hospital, Clinic of Pathology, Adıyaman, Turkey Adıyaman Training and Research Hospital, Clinic of Gastroenterology, Adıyaman, Turkey Introduction:Roasted and spicy food (mainly hot pepper) consumption is very common in Southeastern Anatolia. Smoked and spicy diets and Helicobacter pylori (H. pylori) infection are known risk factors for gastric cancer. The aim of this study was to investigate the effects of eating habits on the gastric mucosa, to investigate the rate of H. pylori positivity, and to examine the association of these factors with histopathological features in this region.Methods:Histopathological findings in endoscopic biopsies of 943 consecutive patients were retrospectively evaluated.Results:More than half of the patients were female (54%; n=505), and the median age was 47±17.27 (range: 18-96). The most common non-gastritis histopathologic diagnosis was gastric carcinoma (2.5%; n=24), followed by polypoid lesions (1.6%; n=16). The vast majority of patients (92%) had chronic gastritis, and neutrophilic activity was present in 61% (n=537). The frequencies of atrophy, intestinal metaplasia, and regenerative mucosal changes were significantly correlated with the severity of neutrophilic activity (p<0.05). Patients with atrophy and intestinal metaplasia were significantly older than those without atrophy and intestinal metaplasia (p<0.001; mean age: 47 and 46 vs 56 and 55, respectively). More than 50% were infected with H. pylori (57%; n=542), and H. pylori positivity was associated with the presence of chronic and chronic active gastritis, as well as lymphoid hyperplasia (p<0.001). In contrast, erosion, atrophy, and neuroendocrine cell hyperplasia were less common in patients with H. pylori gastritis (p<0.05).Conclusion:H. pylori infection and spicy food consumption are key risk factors for gastritis in Southeastern Anatolia. Prospective epidemiological studies are needed to better demonstrate the causal interaction between dietary factors and gastritis. http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/common-findings-in-endoscopic-gastric-biopsies-in-/43922 eating habitsendoscopic biopsygastritishelicobacter pylorihistopathology |
| spellingShingle | Burçin Pehlivanoğlu Bilge Aydın Türk Serap İşler Zülfükar Bilge Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection İstanbul Medical Journal eating habits endoscopic biopsy gastritis helicobacter pylori histopathology |
| title | Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection |
| title_full | Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection |
| title_fullStr | Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection |
| title_full_unstemmed | Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection |
| title_short | Common Findings in Endoscopic Gastric Biopsies in Southeastern Anatolia: Effects of Eating Habits and <italic>Helicobacter Pylori</italic> Infection |
| title_sort | common findings in endoscopic gastric biopsies in southeastern anatolia effects of eating habits and italic helicobacter pylori italic infection |
| topic | eating habits endoscopic biopsy gastritis helicobacter pylori histopathology |
| url |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/common-findings-in-endoscopic-gastric-biopsies-in-/43922
|
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