Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis
Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that leads to a great deterioration in the quality of life. Objective: We aimed to assess the effectiveness of two individual programs, one based on transcranial direct current stimulation (tDCS) and an...
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MDPI AG
2022-12-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/11/1/84 |
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| author | Inés Muñoz-Paredes Azael J. Herrero Natalia Román-Nieto Alba M. Peña-Gomez Jesús Seco-Calvo |
| author_facet | Inés Muñoz-Paredes Azael J. Herrero Natalia Román-Nieto Alba M. Peña-Gomez Jesús Seco-Calvo |
| author_sort | Inés Muñoz-Paredes |
| collection | DOAJ |
| description | Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that leads to a great deterioration in the quality of life. Objective: We aimed to assess the effectiveness of two individual programs, one based on transcranial direct current stimulation (tDCS) and another based on the effect of physical exercise on fatigue and quality of life in patients with MS. Methods: A total of 12 patients with relapsing–remitting and progressive secondary MS participated. Fatigue and quality of life were assessed before and after intervention. The exercise program and tDCS were carried out over a 4-week period, with a washout period of 5 months. Results: The results show significant improvements in the different quality of life subscales after the application of tDCS, activities of daily living (r = 0.625; <i>p</i> = 0.037) (g = 0.465), psychological well-being (r = 0.856; <i>p</i> = 0.004) (g = 0.727) and coping (r = 0.904; <i>p</i> = 0.18) (g = 0.376), and in those after the application of exercise, activities of daily living (r = 0.853; <i>p</i> = 0.003) (g = 0.570) and psychological well-being (r = 0.693; <i>p</i> = 0.041) (g = 0.417). After the application of both therapies, more than 50% of the subjects did not have a positive fatigue score on the MFIS scale. Conclusion: The major findings suggest that the application of both therapies produces a beneficial effect with significant improvements in the quality of life of this sample. |
| first_indexed | 2024-03-11T10:01:18Z |
| format | Article |
| id | doaj.art-c9c7c5930fe649adb0c5d81146c9da12 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-11T10:01:18Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-c9c7c5930fe649adb0c5d81146c9da122023-11-16T15:25:21ZengMDPI AGHealthcare2227-90322022-12-011118410.3390/healthcare11010084Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple SclerosisInés Muñoz-Paredes0Azael J. Herrero1Natalia Román-Nieto2Alba M. Peña-Gomez3Jesús Seco-Calvo4Faculty of Health Sciences, University of León, 24071 León, SpainDepartment of Health Sciences, European University Miguel de Cervantes, 47012 Valladolid, SpainMultiple Sclerosis Association of Palencia, 34004 Palencia, SpainMultiple Sclerosis Association of Palencia, 34004 Palencia, SpainFaculty of Physiotherapy and Nursing, University of Leon, 24071 León, SpainBackground: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that leads to a great deterioration in the quality of life. Objective: We aimed to assess the effectiveness of two individual programs, one based on transcranial direct current stimulation (tDCS) and another based on the effect of physical exercise on fatigue and quality of life in patients with MS. Methods: A total of 12 patients with relapsing–remitting and progressive secondary MS participated. Fatigue and quality of life were assessed before and after intervention. The exercise program and tDCS were carried out over a 4-week period, with a washout period of 5 months. Results: The results show significant improvements in the different quality of life subscales after the application of tDCS, activities of daily living (r = 0.625; <i>p</i> = 0.037) (g = 0.465), psychological well-being (r = 0.856; <i>p</i> = 0.004) (g = 0.727) and coping (r = 0.904; <i>p</i> = 0.18) (g = 0.376), and in those after the application of exercise, activities of daily living (r = 0.853; <i>p</i> = 0.003) (g = 0.570) and psychological well-being (r = 0.693; <i>p</i> = 0.041) (g = 0.417). After the application of both therapies, more than 50% of the subjects did not have a positive fatigue score on the MFIS scale. Conclusion: The major findings suggest that the application of both therapies produces a beneficial effect with significant improvements in the quality of life of this sample.https://www.mdpi.com/2227-9032/11/1/84physical trainingactivities of daily livingModified Fatigue Impact Scale |
| spellingShingle | Inés Muñoz-Paredes Azael J. Herrero Natalia Román-Nieto Alba M. Peña-Gomez Jesús Seco-Calvo Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis Healthcare physical training activities of daily living Modified Fatigue Impact Scale |
| title | Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis |
| title_full | Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis |
| title_fullStr | Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis |
| title_full_unstemmed | Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis |
| title_short | Influence of Transcranial Direct Current Stimulation and Exercise on Fatigue and Quality of Life in Multiple Sclerosis |
| title_sort | influence of transcranial direct current stimulation and exercise on fatigue and quality of life in multiple sclerosis |
| topic | physical training activities of daily living Modified Fatigue Impact Scale |
| url | https://www.mdpi.com/2227-9032/11/1/84 |
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