Integration of the Human Gut Microbiome and Serum Metabolome Reveals Novel Biological Factors Involved in the Regulation of Bone Mineral Density

Integration of the Human Gut Microbiome and Serum Metabolome Reveals Novel Biological Factors Involved in the Regulation of Bone Mineral Density

While the gut microbiome has been reported to play a role in bone metabolism, the individual species and underlying functional mechanisms have not yet been characterized. We conducted a systematic multi-omics analysis using paired metagenomic and untargeted serum metabolomic profiles from a large sa...

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Bibliographic Details
Main Authors: Jonathan Greenbaum, Xu Lin, Kuan-Jui Su, Rui Gong, Hui Shen, Jie Shen, Hong-Mei Xiao, Hong-Wen Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomics
metabolomics
data integration
osteoporosis
bone
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.853499/full

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