Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort
Abstract Background Several studies have verified body fat distribution in association with pulmonary function (PF), mainly waist circumference, but few have used measures able to distinguish abdominal fat compartments. The present study aims to verify the association of visceral adipose tissue (VAT...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-11-01
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| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12890-017-0510-7 |
| _version_ | 1818112083895517184 |
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| author | Paula Duarte de Oliveira Fernando César Wehrmeister Bernardo Lessa Horta Rogelio Pérez-Padilla Giovanny Vinícius Araújo de França Denise P. Gigante Fernando C. Barros Ken K. Ong Emanuella De Lucia Rolfe Ana Maria Baptista Menezes |
| author_facet | Paula Duarte de Oliveira Fernando César Wehrmeister Bernardo Lessa Horta Rogelio Pérez-Padilla Giovanny Vinícius Araújo de França Denise P. Gigante Fernando C. Barros Ken K. Ong Emanuella De Lucia Rolfe Ana Maria Baptista Menezes |
| author_sort | Paula Duarte de Oliveira |
| collection | DOAJ |
| description | Abstract Background Several studies have verified body fat distribution in association with pulmonary function (PF), mainly waist circumference, but few have used measures able to distinguish abdominal fat compartments. The present study aims to verify the association of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with PF measures. Methods In 1982, all hospital births occurring in Pelotas, Brazil, were identified and those livebirths have been followed. In 2012–13, the cohort participants were evaluated and VAT and SAT measured using ultrasound; forced expiratory volume in the first second (FEV1) or forced vital capacity (FVC) were patronized in z-scores stratified by sex. The associations were verified using crude and adjusted linear regressions. Results The present analyses comprised 3438 individuals (1721 women). VAT was inversely associated with spirometric parameters, in both crude and adjusted models. SAT showed inverse associations in the crude analyzes in males and a positive trend after adjustment, except for SAT and FVC in males. To each centimeter of VAT, mean adjusted FEV1 z-scores decreased 0.072 (95% CI -0.107; −0.036) in men and 0.127 (95% CI -0.164; −0.090) in women, and FVC z-scores decreased −0.075 (95% CI -0.111; −0.039) and 0.121 (95% CI -0.158; −0.083), in men and women, respectively. Conclusions VAT has a consistent inverse association with FEV1 and FVC in both sexes. On the other hand, SAT showed inconsistent results with PF parameters. |
| first_indexed | 2024-12-11T03:13:18Z |
| format | Article |
| id | doaj.art-c9c949c674b943a5b0d52e436712af8b |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-12-11T03:13:18Z |
| publishDate | 2017-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-c9c949c674b943a5b0d52e436712af8b2022-12-22T01:22:49ZengBMCBMC Pulmonary Medicine1471-24662017-11-011711810.1186/s12890-017-0510-7Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohortPaula Duarte de Oliveira0Fernando César Wehrmeister1Bernardo Lessa Horta2Rogelio Pérez-Padilla3Giovanny Vinícius Araújo de França4Denise P. Gigante5Fernando C. Barros6Ken K. Ong7Emanuella De Lucia Rolfe8Ana Maria Baptista Menezes9Federal University of Pelotas - Postgraduate Program in EpidemiologyFederal University of Pelotas - Postgraduate Program in EpidemiologyFederal University of Pelotas - Postgraduate Program in EpidemiologyNational Institute of Respiratory DiseasesMinistry of Health - Secretariat of Health SurveillanceFederal University of Pelotas - Postgraduate Program in EpidemiologyCatholic University of Pelotas - Postgraduate Program in Health and BehaviorMedical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical MedicineMedical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical MedicineFederal University of Pelotas - Postgraduate Program in EpidemiologyAbstract Background Several studies have verified body fat distribution in association with pulmonary function (PF), mainly waist circumference, but few have used measures able to distinguish abdominal fat compartments. The present study aims to verify the association of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with PF measures. Methods In 1982, all hospital births occurring in Pelotas, Brazil, were identified and those livebirths have been followed. In 2012–13, the cohort participants were evaluated and VAT and SAT measured using ultrasound; forced expiratory volume in the first second (FEV1) or forced vital capacity (FVC) were patronized in z-scores stratified by sex. The associations were verified using crude and adjusted linear regressions. Results The present analyses comprised 3438 individuals (1721 women). VAT was inversely associated with spirometric parameters, in both crude and adjusted models. SAT showed inverse associations in the crude analyzes in males and a positive trend after adjustment, except for SAT and FVC in males. To each centimeter of VAT, mean adjusted FEV1 z-scores decreased 0.072 (95% CI -0.107; −0.036) in men and 0.127 (95% CI -0.164; −0.090) in women, and FVC z-scores decreased −0.075 (95% CI -0.111; −0.039) and 0.121 (95% CI -0.158; −0.083), in men and women, respectively. Conclusions VAT has a consistent inverse association with FEV1 and FVC in both sexes. On the other hand, SAT showed inconsistent results with PF parameters.http://link.springer.com/article/10.1186/s12890-017-0510-7Pulmonary functionBody compositionAbdominal adiposityVisceral adiposity |
| spellingShingle | Paula Duarte de Oliveira Fernando César Wehrmeister Bernardo Lessa Horta Rogelio Pérez-Padilla Giovanny Vinícius Araújo de França Denise P. Gigante Fernando C. Barros Ken K. Ong Emanuella De Lucia Rolfe Ana Maria Baptista Menezes Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort BMC Pulmonary Medicine Pulmonary function Body composition Abdominal adiposity Visceral adiposity |
| title | Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort |
| title_full | Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort |
| title_fullStr | Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort |
| title_full_unstemmed | Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort |
| title_short | Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort |
| title_sort | visceral and subcutaneous abdominal adiposity and pulmonary function in 30 year old adults a cross sectional analysis nested in a birth cohort |
| topic | Pulmonary function Body composition Abdominal adiposity Visceral adiposity |
| url | http://link.springer.com/article/10.1186/s12890-017-0510-7 |
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