Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction
Collagens are a primary component of the extracellular matrix and are functional ligands for the inhibitory immune receptor leukocyte-associated immunoglobulin-like receptor (LAIR)-1. LAIR-2 is a secreted protein that can act as a decoy receptor by binding collagen with higher affinity than LAIR-1....
| Главные авторы: | , , , , , , , , , , , , , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
eLife Sciences Publications Ltd
2021-06-01
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| Серии: | eLife |
| Предметы: | |
| Online-ссылка: | https://elifesciences.org/articles/62927 |