Recombinant FOXN1 fusion protein increases T cell generation in old mice

T cell development in the thymus is dependent on the thymic microenvironment, in which thymic epithelial cells (TECs) are the major component. However, TECs undergo both a qualitative and quantitative loss during aging, which is believed to be the major factor responsible for age-dependent thymic at...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jin Zhao, Rong Hu, Kuan Chen Lai, Zhenzhen Zhang, Laijun Lai
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2024-07-01
سلاسل:Frontiers in Immunology
الموضوعات:
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423488/full