Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma

Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma

Thyroid hormone receptor-interacting protein 13 (TRIP13) is involved in cancer progression, but its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. Thus, we assessed the expression, functional role, and mechanism of action of TRIP13 in PDAC. We further examined the efficacy of TRIP13 inh...

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Bibliographic Details
Main Authors: Farrukh Afaq, Sumit Agarwal, Prachi Bajpai, Sameer Al Diffalha, Hyung-Gyoon Kim, Shajan Peter, Moh'd Khushman, Subhash C Chauhan, Priyabrata Mukherjee, Sooryanarayana Varambally, Upender Manne
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Pancreatic ductal adenocarcinoma
TRIP13
Tumor progression
Metastasis
Immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558623000751

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