Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis
Purpose: Cytomegalovirus (CMV) has been reported to cause anterior uveitis in the immunocompetent people. Recurrence of this viral uveitis poses a mangement dilemma. With real-time polymerase chain reaction(PCR), it is possible to confirm the clinical diagnosis. We report a case of recurrent CMV ant...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-09-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993618305310 |
| _version_ | 1811220485575278592 |
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| author | Vinita Girish Rao M.K. Janani Jyotirmay Biswas |
| author_facet | Vinita Girish Rao M.K. Janani Jyotirmay Biswas |
| author_sort | Vinita Girish Rao |
| collection | DOAJ |
| description | Purpose: Cytomegalovirus (CMV) has been reported to cause anterior uveitis in the immunocompetent people. Recurrence of this viral uveitis poses a mangement dilemma. With real-time polymerase chain reaction(PCR), it is possible to confirm the clinical diagnosis. We report a case of recurrent CMV anterior uveitis documented by real-time PCR. Observations: A 42 year old man developed PCR proven CMV anterior uveitis. It resolved with oral and topical antivirals but recurred after ten months. The recurrence was controlled by restarting the oral antivirals. Real-time PCR was used to sequentially document the inital infection, the subsequent resolution and the recurrence of the infection. Conclusions and Importance: Real-time PCR is a useful tool in the management of CMV anterior uveitis. Keywords: Cytomegalovirus, Hypertensive anterior uveitis, Real-time polymerase chain reaction |
| first_indexed | 2024-04-12T07:43:41Z |
| format | Article |
| id | doaj.art-c9d1631ec5a14ee2aa725997308467ed |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-04-12T07:43:41Z |
| publishDate | 2019-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-c9d1631ec5a14ee2aa725997308467ed2022-12-22T03:41:46ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362019-09-0115Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitisVinita Girish Rao0M.K. Janani1Jyotirmay Biswas2Corresponding author.; Sankara Nethralaya, College Road, Chennai, Tamil Nadu, IndiaSankara Nethralaya, College Road, Chennai, Tamil Nadu, IndiaSankara Nethralaya, College Road, Chennai, Tamil Nadu, IndiaPurpose: Cytomegalovirus (CMV) has been reported to cause anterior uveitis in the immunocompetent people. Recurrence of this viral uveitis poses a mangement dilemma. With real-time polymerase chain reaction(PCR), it is possible to confirm the clinical diagnosis. We report a case of recurrent CMV anterior uveitis documented by real-time PCR. Observations: A 42 year old man developed PCR proven CMV anterior uveitis. It resolved with oral and topical antivirals but recurred after ten months. The recurrence was controlled by restarting the oral antivirals. Real-time PCR was used to sequentially document the inital infection, the subsequent resolution and the recurrence of the infection. Conclusions and Importance: Real-time PCR is a useful tool in the management of CMV anterior uveitis. Keywords: Cytomegalovirus, Hypertensive anterior uveitis, Real-time polymerase chain reactionhttp://www.sciencedirect.com/science/article/pii/S2451993618305310 |
| spellingShingle | Vinita Girish Rao M.K. Janani Jyotirmay Biswas Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis American Journal of Ophthalmology Case Reports |
| title | Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis |
| title_full | Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis |
| title_fullStr | Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis |
| title_full_unstemmed | Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis |
| title_short | Real-time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis |
| title_sort | real time polymerase chain reaction in recurrent cytomegalovirus anterior uveitis |
| url | http://www.sciencedirect.com/science/article/pii/S2451993618305310 |
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