Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene

Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene

MicroRNA-155 (miR155) is overexpressed in various inflammatory diseases and cancer, in which bone resorption and osteolysis are frequently observed. However, the role of miR155 on osteogenesis and bone mass phenotype is still unknown. Here, we report a low bone mass phenotype in the long bone of Mir...

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Bibliographic Details
Main Authors: Zhichao Zheng, Lihong Wu, Zhicong Li, Ruoshu Tang, Hongtao Li, Yinyin Huang, Tianqi Wang, Shaofen Xu, Haoyu Cheng, Zhitong Ye, Dong Xiao, Xiaolin Lin, Gang Wu, Richard T Jaspers, Janak L Pathak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-01-01
Series:eLife
Subjects:
miR155
bone mass
osteogenesis
S1PR1
cell viability
Online Access:https://elifesciences.org/articles/77742

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