Atrial Natriuretic Peptide Orchestrates a Coordinated Physiological Response to Fuel Non-shivering Thermogenesis

Atrial Natriuretic Peptide Orchestrates a Coordinated Physiological Response to Fuel Non-shivering Thermogenesis

Summary: Atrial natriuretic peptide (ANP) is a cardiac hormone controlling blood volume and pressure in mammals. It is still unclear whether ANP controls cold-induced thermogenesis in vivo. Here, we show that acute cold exposure induces cardiac ANP secretion in mice and humans. Genetic inactivation...

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Main Authors: Deborah Carper, Marine Coué, Emmani B.M. Nascimento, Valentin Barquissau, Damien Lagarde, Carine Pestourie, Claire Laurens, Justine Vily Petit, Maud Soty, Laurent Monbrun, Marie-Adeline Marques, Yannick Jeanson, Yannis Sainte-Marie, Aline Mairal, Sébastien Déjean, Geneviève Tavernier, Nathalie Viguerie, Virginie Bourlier, Frank Lezoualc’h, Audrey Carrière, Wim H.M. Saris, Arne Astrup, Louis Casteilla, Gilles Mithieux, Wouter van Marken Lichtenbelt, Dominique Langin, Patrick Schrauwen, Cedric Moro
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
brown adipose tissue
thermogenesis
uncoupling protein 1
lipolysis
adipocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720310603

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