Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy
Primary cardiac lymphoma (PCL) is a rare disease, the definite diagnosis of which is sometimes difficult and mainly relies on endomyocardial biopsy. Primary cardiac T-cell lymphoma (PCTL) is an extremely rare sub-type of PCL. Here, we report on a 47-year-old female with PCTL who presented with fever...
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.890059/full |
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| author | Panpan Chen Panpan Chen Yuanyuan Hao Yuanyuan Hao Xi Qiu Xi Qiu Xibin Xiao Xibin Xiao Wei Zhu Wei Zhu Yang Xu Yang Xu Wenbin Qian Wenbin Qian |
| author_facet | Panpan Chen Panpan Chen Yuanyuan Hao Yuanyuan Hao Xi Qiu Xi Qiu Xibin Xiao Xibin Xiao Wei Zhu Wei Zhu Yang Xu Yang Xu Wenbin Qian Wenbin Qian |
| author_sort | Panpan Chen |
| collection | DOAJ |
| description | Primary cardiac lymphoma (PCL) is a rare disease, the definite diagnosis of which is sometimes difficult and mainly relies on endomyocardial biopsy. Primary cardiac T-cell lymphoma (PCTL) is an extremely rare sub-type of PCL. Here, we report on a 47-year-old female with PCTL who presented with fever, syncope, palpitations, and a third-degree atrioventricular block (AVB) on electrocardiogram. Chemotherapy was administered with two courses of methotrexate, cyclophosphamide, liposomal doxorubicin, vincristine, and dexamethasone (MTX-CHOP). As the tumor vanished, AVB changed from third degree to second degree and finally to sinus rhythm. In conclusion, endomyocardial biopsy is valuable in the diagnosis of primary cardiac lymphoma. It is worth noting that alterations in the electrocardiogram may indicate an attack on the heart by PCTL. |
| first_indexed | 2024-12-12T06:41:18Z |
| format | Article |
| id | doaj.art-c9d47e027a4a4cbc81db06cf4e4a16a4 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-12T06:41:18Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-c9d47e027a4a4cbc81db06cf4e4a16a42022-12-22T00:34:20ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-06-011310.3389/fimmu.2022.890059890059Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial BiopsyPanpan Chen0Panpan Chen1Yuanyuan Hao2Yuanyuan Hao3Xi Qiu4Xi Qiu5Xibin Xiao6Xibin Xiao7Wei Zhu8Wei Zhu9Yang Xu10Yang Xu11Wenbin Qian12Wenbin Qian13Department of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, ChinaDepartment of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, ChinaDepartment of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, ChinaDepartment of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, ChinaDepartment of Cardiology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaProvincial Key Laboratory of Cardiovascular Research, Hangzhou, ChinaDepartment of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, ChinaDepartment of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, ChinaPrimary cardiac lymphoma (PCL) is a rare disease, the definite diagnosis of which is sometimes difficult and mainly relies on endomyocardial biopsy. Primary cardiac T-cell lymphoma (PCTL) is an extremely rare sub-type of PCL. Here, we report on a 47-year-old female with PCTL who presented with fever, syncope, palpitations, and a third-degree atrioventricular block (AVB) on electrocardiogram. Chemotherapy was administered with two courses of methotrexate, cyclophosphamide, liposomal doxorubicin, vincristine, and dexamethasone (MTX-CHOP). As the tumor vanished, AVB changed from third degree to second degree and finally to sinus rhythm. In conclusion, endomyocardial biopsy is valuable in the diagnosis of primary cardiac lymphoma. It is worth noting that alterations in the electrocardiogram may indicate an attack on the heart by PCTL.https://www.frontiersin.org/articles/10.3389/fimmu.2022.890059/fullprimary cardiac lymphomaT-cell lymphomacomplete atrioventricular blockimmunotherapycase report |
| spellingShingle | Panpan Chen Panpan Chen Yuanyuan Hao Yuanyuan Hao Xi Qiu Xi Qiu Xibin Xiao Xibin Xiao Wei Zhu Wei Zhu Yang Xu Yang Xu Wenbin Qian Wenbin Qian Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy Frontiers in Immunology primary cardiac lymphoma T-cell lymphoma complete atrioventricular block immunotherapy case report |
| title | Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy |
| title_full | Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy |
| title_fullStr | Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy |
| title_full_unstemmed | Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy |
| title_short | Case Report: Primary Cardiac T-Cell Lymphoma With Complete Atrio-Ventricular Block Diagnosed by Endomyocardial Biopsy |
| title_sort | case report primary cardiac t cell lymphoma with complete atrio ventricular block diagnosed by endomyocardial biopsy |
| topic | primary cardiac lymphoma T-cell lymphoma complete atrioventricular block immunotherapy case report |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.890059/full |
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