A microfluidic-based approach to investigate the inflammatory response of macrophages to pristine and drug-loaded nanostructured hydroxyapatite

The in vitro biological characterization of biomaterials is largely based on static cell cultures. However, for highly reactive biomaterials such as calcium-deficient hydroxyapatite (CDHA), this static environment has limitations. Drastic alterations in the ionic composition of the cell culture medi...

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Bibliographic Details
Main Authors: Sarah-Sophia D. Carter, Abdul-Raouf Atif, Anna Diez-Escudero, Maja Grape, Maria-Pau Ginebra, Maria Tenje, Gemma Mestres
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422001491