Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical
A systematic investigation of the electrochemically generated superoxide radical (O2●-) has been conducted in the presence of some flavonoids. Cyclic voltammetry was used to generate O2●- by reducing the molecular oxygen in DMSO at room temperature. The scavenging of the radical was monitored by the...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2012-04-01
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| Series: | Czech Journal of Food Sciences |
| Subjects: | |
| Online Access: | https://cjfs.agriculturejournals.cz/artkey/cjf-201202-0007_antioxidant-activity-coefficient-mechanism-and-kinetics-of-different-derivatives-of-flavones-and-flavanones-t.php |
| _version_ | 1797899769616531456 |
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| author | Safeer AHMED Faria SHAKEEL |
| author_facet | Safeer AHMED Faria SHAKEEL |
| author_sort | Safeer AHMED |
| collection | DOAJ |
| description | A systematic investigation of the electrochemically generated superoxide radical (O2●-) has been conducted in the presence of some flavonoids. Cyclic voltammetry was used to generate O2●- by reducing the molecular oxygen in DMSO at room temperature. The scavenging of the radical was monitored by the decrease in anodic or/and cathodic currents while linearly increasing the concentration of the flavonoid. The strength of interaction was quantified in terms of the binding constant (Kb)values ranging from 1 × 102 and 5 × 103M-1. The antioxidant activity coefficient (Kao) was calculated from the linear part of the plot of 'current decrease vs. flavonoid concentration'. Radical scavenging mechanism of the antioxidant was proposed and discussed in terms of the structure activity relationship. Nicholson-Shain method was employed to estimate the bimolecular homogeneous kinetics and on this basis control use of antioxidant is pointed out. |
| first_indexed | 2024-04-10T08:34:11Z |
| format | Article |
| id | doaj.art-c9daad4033234ae6b1d2b3c8c24e0bf5 |
| institution | Directory Open Access Journal |
| issn | 1212-1800 1805-9317 |
| language | English |
| last_indexed | 2024-04-10T08:34:11Z |
| publishDate | 2012-04-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Czech Journal of Food Sciences |
| spelling | doaj.art-c9daad4033234ae6b1d2b3c8c24e0bf52023-02-23T03:27:52ZengCzech Academy of Agricultural SciencesCzech Journal of Food Sciences1212-18001805-93172012-04-0130215316310.17221/447/2010-CJFScjf-201202-0007Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radicalSafeer AHMED0Faria SHAKEEL1Department of Chemistry, Quaid-i-Azam University, Islamabad, PakistanDepartment of Chemistry, Quaid-i-Azam University, Islamabad, PakistanA systematic investigation of the electrochemically generated superoxide radical (O2●-) has been conducted in the presence of some flavonoids. Cyclic voltammetry was used to generate O2●- by reducing the molecular oxygen in DMSO at room temperature. The scavenging of the radical was monitored by the decrease in anodic or/and cathodic currents while linearly increasing the concentration of the flavonoid. The strength of interaction was quantified in terms of the binding constant (Kb)values ranging from 1 × 102 and 5 × 103M-1. The antioxidant activity coefficient (Kao) was calculated from the linear part of the plot of 'current decrease vs. flavonoid concentration'. Radical scavenging mechanism of the antioxidant was proposed and discussed in terms of the structure activity relationship. Nicholson-Shain method was employed to estimate the bimolecular homogeneous kinetics and on this basis control use of antioxidant is pointed out.https://cjfs.agriculturejournals.cz/artkey/cjf-201202-0007_antioxidant-activity-coefficient-mechanism-and-kinetics-of-different-derivatives-of-flavones-and-flavanones-t.phpantioxidant activity coefficientflavonoidsbinding constanthomogeneous kineticscyclic voltammetry |
| spellingShingle | Safeer AHMED Faria SHAKEEL Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical Czech Journal of Food Sciences antioxidant activity coefficient flavonoids binding constant homogeneous kinetics cyclic voltammetry |
| title | Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical |
| title_full | Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical |
| title_fullStr | Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical |
| title_full_unstemmed | Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical |
| title_short | Antioxidant activity coefficient, mechanism, and kinetics of different derivatives of flavones and flavanones towards superoxide radical |
| title_sort | antioxidant activity coefficient mechanism and kinetics of different derivatives of flavones and flavanones towards superoxide radical |
| topic | antioxidant activity coefficient flavonoids binding constant homogeneous kinetics cyclic voltammetry |
| url | https://cjfs.agriculturejournals.cz/artkey/cjf-201202-0007_antioxidant-activity-coefficient-mechanism-and-kinetics-of-different-derivatives-of-flavones-and-flavanones-t.php |
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