Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis
Background The use of drug-eluting stents (DES) during the percutaneous coronary intervention of patients with degenerated saphenous vein graft (SVG) is uncertain. Although previous studies showed that DES might decrease the rate of re-intervention in patients with SVG stenosis, randomized controlle...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
General Organization of Teaching Hospitals and Institutes
2020-01-01
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| Series: | Journal of Medicine in Scientific Research |
| Subjects: | |
| Online Access: | http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2020;volume=3;issue=2;spage=131;epage=135;aulast=Zayed |
| _version_ | 1827299224942804992 |
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| author | Ahmed Zayed Tamer El Banna Ahmed Algebaly |
| author_facet | Ahmed Zayed Tamer El Banna Ahmed Algebaly |
| author_sort | Ahmed Zayed |
| collection | DOAJ |
| description | Background
The use of drug-eluting stents (DES) during the percutaneous coronary intervention of patients with degenerated saphenous vein graft (SVG) is uncertain. Although previous studies showed that DES might decrease the rate of re-intervention in patients with SVG stenosis, randomized controlled trials comparing bare-metal stents (BMS) and DES in SVG lesions have been inconclusive.
Objective
The purpose of this study was to compare the outcomes in patients undergoing SVG stent implantation treated with DES or BMS.
Patients and methods
This was a retrospective observational study that included 60 patients who underwent percutaneous coronary intervention for SVG lesions, comprising 30 patients who were treated with BMS and 30 patients who were treated with DES at National Heart Institute from March 2015 to March 2018. Three years of outcome and major adverse cardiac event (MACE) were recorded. MACE was defined as death, myocardial infarction (MI), target vessel revascularization, and stroke.
Results
After three years, there was no significant difference between the two groups in MACE. MACE was reported in five (16.6%) patients in the DES group vs eight (26.6%) patients in the BMS group (P>0.05). Death was reported in one (3.3%) patient in each group. MI was reported in two (6.6%) patients in the DES group vs three (10%) patients in the BMS group (P>0.05). One (3.3%) patient developed stroke in the DES group vs two (6.6%) patients in the BMS group (P>0.05). The need for repeat revascularization was reported in one (3.3%) patient in the DES group vs two (6.6%) patients in the BMS group (P>0.05). Stent thrombosis was reported in six (20%) patients in the DES group vs four (13.3%) patients in the BMS group (P>0.05)
Conclusion
Our results in this study showed that there was no significant difference between BMS and DES in patients undergoing percutaneous coronary intervention for SVG lesions for MACE, such as death, target vessel revascularization, and MI. |
| first_indexed | 2024-04-24T15:29:14Z |
| format | Article |
| id | doaj.art-c9db097fe10e49f4ab4259a21c3df79f |
| institution | Directory Open Access Journal |
| issn | 2537-091X 2537-0928 |
| language | English |
| last_indexed | 2024-04-24T15:29:14Z |
| publishDate | 2020-01-01 |
| publisher | General Organization of Teaching Hospitals and Institutes |
| record_format | Article |
| series | Journal of Medicine in Scientific Research |
| spelling | doaj.art-c9db097fe10e49f4ab4259a21c3df79f2024-04-02T05:03:55ZengGeneral Organization of Teaching Hospitals and InstitutesJournal of Medicine in Scientific Research2537-091X2537-09282020-01-013213113510.4103/JMISR.JMISR_10_20Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosisAhmed ZayedTamer El BannaAhmed AlgebalyBackground The use of drug-eluting stents (DES) during the percutaneous coronary intervention of patients with degenerated saphenous vein graft (SVG) is uncertain. Although previous studies showed that DES might decrease the rate of re-intervention in patients with SVG stenosis, randomized controlled trials comparing bare-metal stents (BMS) and DES in SVG lesions have been inconclusive. Objective The purpose of this study was to compare the outcomes in patients undergoing SVG stent implantation treated with DES or BMS. Patients and methods This was a retrospective observational study that included 60 patients who underwent percutaneous coronary intervention for SVG lesions, comprising 30 patients who were treated with BMS and 30 patients who were treated with DES at National Heart Institute from March 2015 to March 2018. Three years of outcome and major adverse cardiac event (MACE) were recorded. MACE was defined as death, myocardial infarction (MI), target vessel revascularization, and stroke. Results After three years, there was no significant difference between the two groups in MACE. MACE was reported in five (16.6%) patients in the DES group vs eight (26.6%) patients in the BMS group (P>0.05). Death was reported in one (3.3%) patient in each group. MI was reported in two (6.6%) patients in the DES group vs three (10%) patients in the BMS group (P>0.05). One (3.3%) patient developed stroke in the DES group vs two (6.6%) patients in the BMS group (P>0.05). The need for repeat revascularization was reported in one (3.3%) patient in the DES group vs two (6.6%) patients in the BMS group (P>0.05). Stent thrombosis was reported in six (20%) patients in the DES group vs four (13.3%) patients in the BMS group (P>0.05) Conclusion Our results in this study showed that there was no significant difference between BMS and DES in patients undergoing percutaneous coronary intervention for SVG lesions for MACE, such as death, target vessel revascularization, and MI.http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2020;volume=3;issue=2;spage=131;epage=135;aulast=Zayedbare-metal stentdrug-eluting stentsaphenous vein graft |
| spellingShingle | Ahmed Zayed Tamer El Banna Ahmed Algebaly Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis Journal of Medicine in Scientific Research bare-metal stent drug-eluting stent saphenous vein graft |
| title | Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis |
| title_full | Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis |
| title_fullStr | Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis |
| title_full_unstemmed | Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis |
| title_short | Comparison of drug-eluting and bare-metal stents in patients with saphenous vein graft stenosis |
| title_sort | comparison of drug eluting and bare metal stents in patients with saphenous vein graft stenosis |
| topic | bare-metal stent drug-eluting stent saphenous vein graft |
| url | http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2020;volume=3;issue=2;spage=131;epage=135;aulast=Zayed |
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