Review of selected herbal phytoconstituents for potential melanoma treatment
Malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. The current chemotherapies have a relatively low success rate due to the development of multidrug resistance and side effects. Hence, there is need of discovering new compounds that are safe and more effective...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Health Sciences and Biomedical Research KLEU |
| Subjects: | |
| Online Access: | http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2018;volume=11;issue=1;spage=3;epage=11;aulast=Kurangi |
| _version_ | 1819100485493194752 |
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| author | Bhaskar Kallappa Kurangi Sunil Satyappa Jalalpure |
| author_facet | Bhaskar Kallappa Kurangi Sunil Satyappa Jalalpure |
| author_sort | Bhaskar Kallappa Kurangi |
| collection | DOAJ |
| description | Malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. The current chemotherapies have a relatively low success rate due to the development of multidrug resistance and side effects. Hence, there is need of discovering new compounds that are safe and more effective against melanoma to improve the efficiency and to lower the treatment cost for cancer care. Melanoma chemoprevention with natural herbal phytoconstituents is an emerging strategy to prevent, cure, or treat melanoma. This review summarizes the latest research in melanoma chemoprevention and treatment using the herbal phytoconstituents. Relevant mechanisms involved in the pharmacological effects of these phytochemical are discussed. Phytoconstituents that are discussed in this review are carotenoids, flavonoids, some polyphenols, piperine alkaloid, and sulforaphane having high anticancer potential mostly to be used for the treatment of melanoma. |
| first_indexed | 2024-12-22T01:03:31Z |
| format | Article |
| id | doaj.art-c9de743257064940abe139dbd9eac231 |
| institution | Directory Open Access Journal |
| issn | 2542-6214 2542-6222 |
| language | English |
| last_indexed | 2024-12-22T01:03:31Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Health Sciences and Biomedical Research KLEU |
| spelling | doaj.art-c9de743257064940abe139dbd9eac2312022-12-21T18:44:08ZengWolters Kluwer Medknow PublicationsIndian Journal of Health Sciences and Biomedical Research KLEU2542-62142542-62222018-01-0111131110.4103/kleuhsj.kleuhsj_319_17Review of selected herbal phytoconstituents for potential melanoma treatmentBhaskar Kallappa KurangiSunil Satyappa JalalpureMalignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. The current chemotherapies have a relatively low success rate due to the development of multidrug resistance and side effects. Hence, there is need of discovering new compounds that are safe and more effective against melanoma to improve the efficiency and to lower the treatment cost for cancer care. Melanoma chemoprevention with natural herbal phytoconstituents is an emerging strategy to prevent, cure, or treat melanoma. This review summarizes the latest research in melanoma chemoprevention and treatment using the herbal phytoconstituents. Relevant mechanisms involved in the pharmacological effects of these phytochemical are discussed. Phytoconstituents that are discussed in this review are carotenoids, flavonoids, some polyphenols, piperine alkaloid, and sulforaphane having high anticancer potential mostly to be used for the treatment of melanoma.http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2018;volume=11;issue=1;spage=3;epage=11;aulast=KurangiAnticancerchemopreventionmelanomaphytoconstituents |
| spellingShingle | Bhaskar Kallappa Kurangi Sunil Satyappa Jalalpure Review of selected herbal phytoconstituents for potential melanoma treatment Indian Journal of Health Sciences and Biomedical Research KLEU Anticancer chemoprevention melanoma phytoconstituents |
| title | Review of selected herbal phytoconstituents for potential melanoma treatment |
| title_full | Review of selected herbal phytoconstituents for potential melanoma treatment |
| title_fullStr | Review of selected herbal phytoconstituents for potential melanoma treatment |
| title_full_unstemmed | Review of selected herbal phytoconstituents for potential melanoma treatment |
| title_short | Review of selected herbal phytoconstituents for potential melanoma treatment |
| title_sort | review of selected herbal phytoconstituents for potential melanoma treatment |
| topic | Anticancer chemoprevention melanoma phytoconstituents |
| url | http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2018;volume=11;issue=1;spage=3;epage=11;aulast=Kurangi |
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