Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases
Liver diseases are the major predisposing conditions for the development of malnutrition, sarcopenia, and frailty. Recently, the mechanism of the onset of these complications has been better established. Regardless of the etiology of the underlying liver disease, the clinical manifestations are comm...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/15/3487 |
| _version_ | 1797586190258405376 |
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| author | Silvia Espina Diego Casas-Deza Vanesa Bernal-Monterde María José Domper-Arnal Sandra García-Mateo Alberto Lué |
| author_facet | Silvia Espina Diego Casas-Deza Vanesa Bernal-Monterde María José Domper-Arnal Sandra García-Mateo Alberto Lué |
| author_sort | Silvia Espina |
| collection | DOAJ |
| description | Liver diseases are the major predisposing conditions for the development of malnutrition, sarcopenia, and frailty. Recently, the mechanism of the onset of these complications has been better established. Regardless of the etiology of the underlying liver disease, the clinical manifestations are common. The main consequences are impaired dietary intake, altered macro- and micronutrient metabolism, energy metabolism disturbances, an increase in energy expenditure, nutrient malabsorption, sarcopenia, frailty, and osteopathy. These complications have direct effects on clinical outcomes, survival, and quality of life. The nutritional status should be assessed systematically and periodically during follow-up in these patients. Maintaining and preserving an adequate nutritional status is crucial and should be a mainstay of treatment. Although general nutritional interventions have been established, special considerations are needed in specific settings such as decompensated cirrhosis, alcohol-related liver disease, and metabolic-dysfunction-associated fatty liver disease. In this review, we summarize the physiopathology and factors that impact the nutritional status of liver disease. We review how to assess malnutrition and sarcopenia and how to prevent and manage these complications in this setting. |
| first_indexed | 2024-03-11T00:19:55Z |
| format | Article |
| id | doaj.art-c9e041a17ee44f5db58ccf025228149d |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T00:19:55Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-c9e041a17ee44f5db58ccf025228149d2023-11-18T23:25:15ZengMDPI AGNutrients2072-66432023-08-011515348710.3390/nu15153487Evaluation and Management of Nutritional Consequences of Chronic Liver DiseasesSilvia Espina0Diego Casas-Deza1Vanesa Bernal-Monterde2María José Domper-Arnal3Sandra García-Mateo4Alberto Lué5Gastroenterology Department, Miguel Servet University Hospital, 50009 Zaragoza, SpainGastroenterology Department, Miguel Servet University Hospital, 50009 Zaragoza, SpainGastroenterology Department, Miguel Servet University Hospital, 50009 Zaragoza, SpainInstituto de Investigación Sanitaria (IIS) Aragon, 50009 Zaragoza, SpainInstituto de Investigación Sanitaria (IIS) Aragon, 50009 Zaragoza, SpainInstituto de Investigación Sanitaria (IIS) Aragon, 50009 Zaragoza, SpainLiver diseases are the major predisposing conditions for the development of malnutrition, sarcopenia, and frailty. Recently, the mechanism of the onset of these complications has been better established. Regardless of the etiology of the underlying liver disease, the clinical manifestations are common. The main consequences are impaired dietary intake, altered macro- and micronutrient metabolism, energy metabolism disturbances, an increase in energy expenditure, nutrient malabsorption, sarcopenia, frailty, and osteopathy. These complications have direct effects on clinical outcomes, survival, and quality of life. The nutritional status should be assessed systematically and periodically during follow-up in these patients. Maintaining and preserving an adequate nutritional status is crucial and should be a mainstay of treatment. Although general nutritional interventions have been established, special considerations are needed in specific settings such as decompensated cirrhosis, alcohol-related liver disease, and metabolic-dysfunction-associated fatty liver disease. In this review, we summarize the physiopathology and factors that impact the nutritional status of liver disease. We review how to assess malnutrition and sarcopenia and how to prevent and manage these complications in this setting.https://www.mdpi.com/2072-6643/15/15/3487malnutritionsarcopeniafrailtycirrhosisalcohol-related liver diseasemetabolic dysfunction-associated fatty liver disease |
| spellingShingle | Silvia Espina Diego Casas-Deza Vanesa Bernal-Monterde María José Domper-Arnal Sandra García-Mateo Alberto Lué Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases Nutrients malnutrition sarcopenia frailty cirrhosis alcohol-related liver disease metabolic dysfunction-associated fatty liver disease |
| title | Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases |
| title_full | Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases |
| title_fullStr | Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases |
| title_full_unstemmed | Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases |
| title_short | Evaluation and Management of Nutritional Consequences of Chronic Liver Diseases |
| title_sort | evaluation and management of nutritional consequences of chronic liver diseases |
| topic | malnutrition sarcopenia frailty cirrhosis alcohol-related liver disease metabolic dysfunction-associated fatty liver disease |
| url | https://www.mdpi.com/2072-6643/15/15/3487 |
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