The establishment of polypeptide PSMA‐targeted chimeric antigen receptor‐engineered natural killer cells for castration‐resistant prostate cancer and the induction of ferroptosis‐related cell death

The establishment of polypeptide PSMA‐targeted chimeric antigen receptor‐engineered natural killer cells for castration‐resistant prostate cancer and the induction of ferroptosis‐related cell death

Abstract Background The mortality of castration‐resistant prostate cancer (CRPC) is high due to lack of an effective treatment. Chimeric antigen receptor (CAR)‐based therapy is a promising immunotherapeutic strategy. Here, we aimed to design a novel CAR‐natural killer (NK) cells with a clinically si...

Full description

Bibliographic Details
Main Authors: Liyuan Wu, Fei Liu, Le Yin, Fangming Wang, Hui Shi, Qinxin Zhao, Feiya Yang, Dong Chen, Xiying Dong, Yuchun Gu, Nianzeng Xing
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Cancer Communications
Subjects:
CAR‐NK92MI
chimeric antigen receptors
immunotherapy
prostate‐specific membrane antigen ferroptosis
Online Access:https://doi.org/10.1002/cac2.12321

Similar Items

Similar Items