Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid
The main goal of this study is to elaborate and evaluate the physicochemical properties of the synthetic biphasic calcium phosphate (BCP) powder: an associate compound of hydroxyapatite (HA): Ca10(PO4)6(OH)2 and beta-tricalcium phosphate (β-TCP): Ca3(PO4)2. The new compound BCP has two advantages: h...
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| Format: | Article |
| Language: | English |
| Published: |
Universiti Brunei Darussalam
2016-12-01
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| Series: | ASEAN Journal on Science and Technology for Development |
| Subjects: | |
| Online Access: | http://www.ajstd.org/index.php/ajstd/article/view/30 |
| _version_ | 1797331506843090944 |
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| author | X.V Bui T.D Thang |
| author_facet | X.V Bui T.D Thang |
| author_sort | X.V Bui |
| collection | DOAJ |
| description | The main goal of this study is to elaborate and evaluate the physicochemical properties of the synthetic biphasic calcium phosphate (BCP) powder: an associate compound of hydroxyapatite (HA): Ca10(PO4)6(OH)2 and beta-tricalcium phosphate (β-TCP): Ca3(PO4)2. The new compound BCP has two advantages: high bioactivity (HA) and fast biodegradation (β-TCP). The obtained powder of BCP was prepared by the precipitate method. XRD analysis confirmed the synthetic material contained both HA and β-TCP crystalline phases. SEM images showed that the small particles of HA attached to bigger particles of β-TCP in the structure morphology of BCP. The in vitro experiment was carried out in static condition by soaking of a series of 50 mg BCP powder in 100 ml of simulated body fluid solution at different period of soaking time. The XRD and SEM methods studied the microstructure
and chemical bond after soaking. The obtained results confirmed the bioactivity of synthetic BCP material by the formation of a new apatite layer on its surface. |
| first_indexed | 2024-03-08T07:35:34Z |
| format | Article |
| id | doaj.art-c9e8741d0c7e4941b7a3a2dd7923de72 |
| institution | Directory Open Access Journal |
| issn | 0217-5460 2224-9028 |
| language | English |
| last_indexed | 2024-03-08T07:35:34Z |
| publishDate | 2016-12-01 |
| publisher | Universiti Brunei Darussalam |
| record_format | Article |
| series | ASEAN Journal on Science and Technology for Development |
| spelling | doaj.art-c9e8741d0c7e4941b7a3a2dd7923de722024-02-02T19:08:58ZengUniversiti Brunei DarussalamASEAN Journal on Science and Technology for Development0217-54602224-90282016-12-01332386810.29037/ajstd.3030Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body FluidX.V Bui0T.D Thang1Ton Duc Thang University, No. 19 Nguyen Huu Tho Street, Tan Phong Ward, District 7, Ho Chi Minh CityHo Chi Minh City Industry and Trade College, No. 20 Tang Nhon Phu Street, Phuoc Long B Ward, District 9, Ho Chi Minh CityThe main goal of this study is to elaborate and evaluate the physicochemical properties of the synthetic biphasic calcium phosphate (BCP) powder: an associate compound of hydroxyapatite (HA): Ca10(PO4)6(OH)2 and beta-tricalcium phosphate (β-TCP): Ca3(PO4)2. The new compound BCP has two advantages: high bioactivity (HA) and fast biodegradation (β-TCP). The obtained powder of BCP was prepared by the precipitate method. XRD analysis confirmed the synthetic material contained both HA and β-TCP crystalline phases. SEM images showed that the small particles of HA attached to bigger particles of β-TCP in the structure morphology of BCP. The in vitro experiment was carried out in static condition by soaking of a series of 50 mg BCP powder in 100 ml of simulated body fluid solution at different period of soaking time. The XRD and SEM methods studied the microstructure and chemical bond after soaking. The obtained results confirmed the bioactivity of synthetic BCP material by the formation of a new apatite layer on its surface.http://www.ajstd.org/index.php/ajstd/article/view/30High bioactivitybeta-tricalcium phosphatebiphasic calcium phosphatebioactivitysimulated body fluid |
| spellingShingle | X.V Bui T.D Thang Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid ASEAN Journal on Science and Technology for Development High bioactivity beta-tricalcium phosphate biphasic calcium phosphate bioactivity simulated body fluid |
| title | Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid |
| title_full | Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid |
| title_fullStr | Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid |
| title_full_unstemmed | Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid |
| title_short | Synthesis of Biphasic Calcium Phosphate and its Behaviour in Simulated Body Fluid |
| title_sort | synthesis of biphasic calcium phosphate and its behaviour in simulated body fluid |
| topic | High bioactivity beta-tricalcium phosphate biphasic calcium phosphate bioactivity simulated body fluid |
| url | http://www.ajstd.org/index.php/ajstd/article/view/30 |
| work_keys_str_mv | AT xvbui synthesisofbiphasiccalciumphosphateanditsbehaviourinsimulatedbodyfluid AT tdthang synthesisofbiphasiccalciumphosphateanditsbehaviourinsimulatedbodyfluid |