Identification of human phosphoglycerate mutase 1 (PGAM1) inhibitors using hybrid virtual screening approaches

PGAM1 plays a critical role in cancer cell metabolism through glycolysis and different biosynthesis pathways to promote cancer. It is generally known as a crucial target for treating pancreatic ductal adenocarcinoma, the deadliest known malignancy worldwide. In recent years different studies have be...

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Bibliographic Details
Main Authors: Numan Yousaf, Rima D. Alharthy, Maryam, Iqra Kamal, Muhammad Saleem, Muhammad Muddassar
Format: Article
Language:English
Published: PeerJ Inc. 2023-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/14936.pdf