Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair
Endometrial injury is the main fact leading to infertility. Current treatments of endometrial injury present many problems, such as unable to achieve desired effects due to low retention and the inherent potential risk of injury. Besides, it is important to the development of bioinspired material th...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.1013217/full |
| _version_ | 1811210407730216960 |
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| author | Rong Dong Saihua Ma Xiaoli Zhao Baojuan Wang Mridul Roy Lu Yao Tian Xia Yanting Liu |
| author_facet | Rong Dong Saihua Ma Xiaoli Zhao Baojuan Wang Mridul Roy Lu Yao Tian Xia Yanting Liu |
| author_sort | Rong Dong |
| collection | DOAJ |
| description | Endometrial injury is the main fact leading to infertility. Current treatments of endometrial injury present many problems, such as unable to achieve desired effects due to low retention and the inherent potential risk of injury. Besides, it is important to the development of bioinspired material that can mimic the natural tissue and possess native tissue topography. Hydrogel is a kind of bioinspired superhydrophilic materials with unique characteristics, such as excellent biocompatibility, biodegradability, porosity, swelling, and cross-linkage. These unique physiochemical properties of bioinspired hydrogels enable their promising application as novel delivery platform and alternative therapies for endometrial injury. In this mini review, we summarize the recent advances in bioinispred hydrogel-based delivery system for endometrial repair, including as a post-operative physical barrier and therapeutic delivery system. In addition, present status, limitations, and future perspectives are also discussed. |
| first_indexed | 2024-04-12T04:55:05Z |
| format | Article |
| id | doaj.art-c9ee24c22b894e1fb6c11e4af7f38740 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-12T04:55:05Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-c9ee24c22b894e1fb6c11e4af7f387402022-12-22T03:47:10ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-09-011010.3389/fbioe.2022.10132171013217Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repairRong Dong0Saihua Ma1Xiaoli Zhao2Baojuan Wang3Mridul Roy4Lu Yao5Tian Xia6Yanting Liu7First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, ChinaHemay Zhihui Science and Technology Co. Ltd, Tianjin, ChinaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, ChinaEndometrial injury is the main fact leading to infertility. Current treatments of endometrial injury present many problems, such as unable to achieve desired effects due to low retention and the inherent potential risk of injury. Besides, it is important to the development of bioinspired material that can mimic the natural tissue and possess native tissue topography. Hydrogel is a kind of bioinspired superhydrophilic materials with unique characteristics, such as excellent biocompatibility, biodegradability, porosity, swelling, and cross-linkage. These unique physiochemical properties of bioinspired hydrogels enable their promising application as novel delivery platform and alternative therapies for endometrial injury. In this mini review, we summarize the recent advances in bioinispred hydrogel-based delivery system for endometrial repair, including as a post-operative physical barrier and therapeutic delivery system. In addition, present status, limitations, and future perspectives are also discussed.https://www.frontiersin.org/articles/10.3389/fbioe.2022.1013217/fullbioinspiredhydrogeluterineendometrialreproductive |
| spellingShingle | Rong Dong Saihua Ma Xiaoli Zhao Baojuan Wang Mridul Roy Lu Yao Tian Xia Yanting Liu Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair Frontiers in Bioengineering and Biotechnology bioinspired hydrogel uterine endometrial reproductive |
| title | Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair |
| title_full | Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair |
| title_fullStr | Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair |
| title_full_unstemmed | Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair |
| title_short | Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair |
| title_sort | recent progress of bioinspired hydrogel based delivery system for endometrial repair |
| topic | bioinspired hydrogel uterine endometrial reproductive |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.1013217/full |
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