Carcinogenesis and Metastasis: Focus on TRPV1-Positive Neurons and Immune Cells
Both sensory neurons and immune cells, albeit at markedly different levels, express the vanilloid (capsaicin) receptor, Transient Receptor Potential, Vanilloid-1 (TRPV1). Activation of TRPV1 channels in sensory afferent nerve fibers induces local effector functions by releasing neuropeptides (most n...
Main Authors: | Nuray Erin, Arpad Szallasi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-06-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/13/6/983 |
Similar Items
-
Molecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons
by: László Pecze, et al.
Published: (2017-06-01) -
Trafficking of ThermoTRP Channels
by: Clotilde Ferrandiz-Huertas, et al.
Published: (2014-08-01) -
Positive allosteric modulation of TRPV1 as a novel analgesic mechanism
by: Lebovitz Evan E, et al.
Published: (2012-09-01) -
Streptozotocin-Induced Early Thermal Hyperalgesia is independent of Glycemic State of Rats: Role of Transient Receptor Potential Vanilloid 1(TRPV1) and Inflammatory mediators
by: Zhong Linlin, et al.
Published: (2011-07-01) -
Unveiling the mechanisms of neuropathic pain suppression: perineural resiniferatoxin targets Trpv1 and beyond
by: Safa Shehab, et al.
Published: (2023-11-01)