Update on the management of chronic rhinosinusitis
Rachel B Cain, Devyani LalDepartment of Otorhinolaryngology, Mayo Clinic, Phoenix, AZ, USAAbstract: Chronic rhinosinusitis (CRS) is a common disorder characterized by mucosal inflammation of the nose and paranasal sinuses with sinonasal symptoms persisting for greater than 12 weeks. The etiology of...
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2013-01-01
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| Series: | Infection and Drug Resistance |
| Online Access: | http://www.dovepress.com/update-on-the-management-of-chronic-rhinosinusitis-a12043 |
| _version_ | 1811200782948630528 |
|---|---|
| author | Cain RB Lal D |
| author_facet | Cain RB Lal D |
| author_sort | Cain RB |
| collection | DOAJ |
| description | Rachel B Cain, Devyani LalDepartment of Otorhinolaryngology, Mayo Clinic, Phoenix, AZ, USAAbstract: Chronic rhinosinusitis (CRS) is a common disorder characterized by mucosal inflammation of the nose and paranasal sinuses with sinonasal symptoms persisting for greater than 12 weeks. The etiology of CRS is incompletely understood. Current understanding supports inflammation, rather than infection, as the dominant etiologic factor. CRS significantly impacts patients' quality of life and health care expenditure. There is no standard management of CRS. Treatment strategies differ based on divergent etiologies of the various CRS subclasses. Both systemic and topical agents are used. These interventions differ in CRS with nasal polyposis (CRSwNP), CRS without nasal polyposis (CRSsNP) and specific situations such as allergic fungal rhinosinusitis or aspirin-exacerbated respiratory disease. Antibiotics are the most commonly prescribed medication for CRS, but their role in management is not strongly supported by high-level studies. This paper provides a succinct review of the evidence supporting or refuting common therapeutic agents in the management of CRS. Novel and emerging strategies will also be discussed.Keywords: review, evidence-based, sinusitis |
| first_indexed | 2024-04-12T02:09:28Z |
| format | Article |
| id | doaj.art-c9f1772ae7d946ff9181de9ec20a5a0e |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-04-12T02:09:28Z |
| publishDate | 2013-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-c9f1772ae7d946ff9181de9ec20a5a0e2022-12-22T03:52:26ZengDove Medical PressInfection and Drug Resistance1178-69732013-01-012013default114Update on the management of chronic rhinosinusitisCain RBLal DRachel B Cain, Devyani LalDepartment of Otorhinolaryngology, Mayo Clinic, Phoenix, AZ, USAAbstract: Chronic rhinosinusitis (CRS) is a common disorder characterized by mucosal inflammation of the nose and paranasal sinuses with sinonasal symptoms persisting for greater than 12 weeks. The etiology of CRS is incompletely understood. Current understanding supports inflammation, rather than infection, as the dominant etiologic factor. CRS significantly impacts patients' quality of life and health care expenditure. There is no standard management of CRS. Treatment strategies differ based on divergent etiologies of the various CRS subclasses. Both systemic and topical agents are used. These interventions differ in CRS with nasal polyposis (CRSwNP), CRS without nasal polyposis (CRSsNP) and specific situations such as allergic fungal rhinosinusitis or aspirin-exacerbated respiratory disease. Antibiotics are the most commonly prescribed medication for CRS, but their role in management is not strongly supported by high-level studies. This paper provides a succinct review of the evidence supporting or refuting common therapeutic agents in the management of CRS. Novel and emerging strategies will also be discussed.Keywords: review, evidence-based, sinusitishttp://www.dovepress.com/update-on-the-management-of-chronic-rhinosinusitis-a12043 |
| spellingShingle | Cain RB Lal D Update on the management of chronic rhinosinusitis Infection and Drug Resistance |
| title | Update on the management of chronic rhinosinusitis |
| title_full | Update on the management of chronic rhinosinusitis |
| title_fullStr | Update on the management of chronic rhinosinusitis |
| title_full_unstemmed | Update on the management of chronic rhinosinusitis |
| title_short | Update on the management of chronic rhinosinusitis |
| title_sort | update on the management of chronic rhinosinusitis |
| url | http://www.dovepress.com/update-on-the-management-of-chronic-rhinosinusitis-a12043 |
| work_keys_str_mv | AT cainrb updateonthemanagementofchronicrhinosinusitis AT lald updateonthemanagementofchronicrhinosinusitis |