Toxoplasma gondii Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway

Toxoplasma gondii Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway

Toxoplasma gondii infects almost all warm-blooded animals, including humans, leading to both cellular and humoral immune responses in the host. The virulence of T. gondii is strain specific and is defined by secreted effector proteins that disturb host immunity. Here, we focus on nuclear factor-kapp...

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Bibliographic Details
Main Authors: Fumiaki Ihara, Ragab M. Fereig, Yuu Himori, Kyohko Kameyama, Kosuke Umeda, Sachi Tanaka, Rina Ikeda, Masahiro Yamamoto, Yoshifumi Nishikawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
dense granule protein
NFκB
immune response
host-pathogen interaction
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01709/full

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