Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment

Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment

Anti-tuberculosis drug treatment is known to affect the number, phenotype, and effector functionality of antigen-specific T-cells. In order to objectively gauge Mycobacterium tuberculosis (MTB)-specific CD8+ T-cells at the single-cell level, we developed soluble major histocompatibility complex (MHC...

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Bibliographic Details
Main Authors:	Rebecca Axelsson-Robertson, Martin Rao, Andre G. Loxton, Gerhard Walzl, Matthew Bates, Alimuddin Zumla, Markus Maeurer
Format:	Article
Language:	English
Published:	Elsevier 2015-03-01
Series:	International Journal of Infectious Diseases
Subjects:	CD8+ T-cells Mycobacterium tuberculosis Tetramers Multimers MHC
Online Access:	http://www.sciencedirect.com/science/article/pii/S1201971215000235

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