The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer
As of November 2023, 140 World Health Organization (WHO) member states had introduced human papillomavirus (HPV) vaccination in their routine immunization schedules. Despite a continuously increasing demand from countries across all income groups, supply constraints, COVID-19 pandemic disruptions, a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/12/1/4 |
| _version_ | 1797339366642679808 |
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| author | Stefano Malvolti Adam Soble Paul Bloem D Scott LaMontagne Rakesh Aggarwal Punnee Pitisuttithum Helen Rees Tania Cernuschi |
| author_facet | Stefano Malvolti Adam Soble Paul Bloem D Scott LaMontagne Rakesh Aggarwal Punnee Pitisuttithum Helen Rees Tania Cernuschi |
| author_sort | Stefano Malvolti |
| collection | DOAJ |
| description | As of November 2023, 140 World Health Organization (WHO) member states had introduced human papillomavirus (HPV) vaccination in their routine immunization schedules. Despite a continuously increasing demand from countries across all income groups, supply constraints, COVID-19 pandemic disruptions, and other factors have slowed the pace of introduction, particularly in low-resource settings. Using a population-based forecasting methodology and leveraging the WHO’s yearly vaccine supply data collection, we updated global demand and supply projections for the HPV vaccine for the period of 2022–2031. The analysis aimed at clarifying the magnitude of the challenges to bringing in equitable access to HPV vaccines, which can hinder the achievement of the Global Strategy for the Elimination of Cervical Cancer. The results of this analysis show that the risk of HPV shortages has significantly decreased, and global supply is now, under normal circumstances, sufficient to meet global demand. In the long term, HPV supply will be more than sufficient to meet the Global Strategy’s goal of 90% of girls fully vaccinated with the HPV vaccine by the age of 15 years. Nonetheless, paying attention to the formulation of policies and carefully managing demand and supply will be required to ensure the long-term sustainability of the HPV vaccine program. |
| first_indexed | 2024-03-08T09:45:00Z |
| format | Article |
| id | doaj.art-c9f677cb802d42b981c4dd798b172c69 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-08T09:45:00Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-c9f677cb802d42b981c4dd798b172c692024-01-29T14:25:06ZengMDPI AGVaccines2076-393X2023-12-01121410.3390/vaccines12010004The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical CancerStefano Malvolti0Adam Soble1Paul Bloem2D Scott LaMontagne3Rakesh Aggarwal4Punnee Pitisuttithum5Helen Rees6Tania Cernuschi7MMGH Consulting GmbH, 8049 Zurich, SwitzerlandMMGH Consulting GmbH, 8049 Zurich, SwitzerlandDepartment of Immunization, Vaccines and Biologicals, World Health Organization, 1202 Geneva, SwitzerlandJohn Snow, Inc. (JSI), Arlington, VA 22202, USAJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry 605006, IndiaFaculty of Tropical Medicine, Mahidol University, Bangkok 10400, ThailandWits RHI, University of Witwatersrand, Johannesburg 2001, South AfricaDepartment of Immunization, Vaccines and Biologicals, World Health Organization, 1202 Geneva, SwitzerlandAs of November 2023, 140 World Health Organization (WHO) member states had introduced human papillomavirus (HPV) vaccination in their routine immunization schedules. Despite a continuously increasing demand from countries across all income groups, supply constraints, COVID-19 pandemic disruptions, and other factors have slowed the pace of introduction, particularly in low-resource settings. Using a population-based forecasting methodology and leveraging the WHO’s yearly vaccine supply data collection, we updated global demand and supply projections for the HPV vaccine for the period of 2022–2031. The analysis aimed at clarifying the magnitude of the challenges to bringing in equitable access to HPV vaccines, which can hinder the achievement of the Global Strategy for the Elimination of Cervical Cancer. The results of this analysis show that the risk of HPV shortages has significantly decreased, and global supply is now, under normal circumstances, sufficient to meet global demand. In the long term, HPV supply will be more than sufficient to meet the Global Strategy’s goal of 90% of girls fully vaccinated with the HPV vaccine by the age of 15 years. Nonetheless, paying attention to the formulation of policies and carefully managing demand and supply will be required to ensure the long-term sustainability of the HPV vaccine program.https://www.mdpi.com/2076-393X/12/1/4human papilloma virusvaccinedemand forecastsupplycervical cancer |
| spellingShingle | Stefano Malvolti Adam Soble Paul Bloem D Scott LaMontagne Rakesh Aggarwal Punnee Pitisuttithum Helen Rees Tania Cernuschi The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer Vaccines human papilloma virus vaccine demand forecast supply cervical cancer |
| title | The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer |
| title_full | The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer |
| title_fullStr | The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer |
| title_full_unstemmed | The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer |
| title_short | The Global Demand and Supply Balance of the Human Papillomavirus Vaccine: Implications for the Global Strategy for the Elimination of Cervical Cancer |
| title_sort | global demand and supply balance of the human papillomavirus vaccine implications for the global strategy for the elimination of cervical cancer |
| topic | human papilloma virus vaccine demand forecast supply cervical cancer |
| url | https://www.mdpi.com/2076-393X/12/1/4 |
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