Distinct Phospho-TDP-43 brain distribution in two cases of FTD, one associated with ALS
ABSTRACT INTRODUCTION: TDP-43 is an intranuclear protein involved in many cellular processes. When altered, it shows a change in pattern of distribution, as well as in functioning, throughout the Central Nervous System structures. Frontotemporal Lobar Degeneration (FTLD) and Amyotrophic Lateral Scl...
Main Authors: | Álvaro C.B. Guedes, Ricardo Santin, André S.R. Costa, Keli C. Reiter, Arlete Hilbig, Liana L. Fernandez |
---|---|
Format: | Article |
Language: | English |
Published: |
Associação Neurologia Cognitiva e do Comportamento
|
Series: | Dementia & Neuropsychologia |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000300249&lng=en&tlng=en |
Similar Items
-
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD
by: Tariq Afroz, et al.
Published: (2023-04-01) -
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD
by: Elodie Chevalier, et al.
Published: (2024-10-01) -
TDP-43 Proteinopathy Specific Biomarker Development
by: Isabell Cordts, et al.
Published: (2023-02-01) -
Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis
by: Rachel H. Tan, et al.
Published: (2023-11-01) -
Cyclin F can alter the turnover of TDP-43
by: Stephanie L. Rayner, et al.
Published: (2024-03-01)