Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.

Introduction Optimal triage strategies for patients suspected of acute ischemic stroke due to large vessel occlusion remains debated. Whereas secondary analyses from randomized trials have demonstrated no differences in thrombectomy outcomes in transferred vs direct presentation strokes (1‐2), sever...

Full description

Bibliographic Details
Main Authors: Mohammad H. Abbasi, Steven Warach, Hamidreza Saber
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Stroke: Vascular and Interventional Neurology
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.057
_version_ 1797221239692984320
author Mohammad H. Abbasi
Steven Warach
Hamidreza Saber
author_facet Mohammad H. Abbasi
Steven Warach
Hamidreza Saber
author_sort Mohammad H. Abbasi
collection DOAJ
description Introduction Optimal triage strategies for patients suspected of acute ischemic stroke due to large vessel occlusion remains debated. Whereas secondary analyses from randomized trials have demonstrated no differences in thrombectomy outcomes in transferred vs direct presentation strokes (1‐2), several registry based cohorts reported worse functional outcomes in those with transferred presentation mode (3‐4). We explored the US national claims database to explore trends in presentation (transferred vs direct presentation) and their outcomes for EVT hospitalizations using a nationally representative sample. Methods National Inpatient Sample database was retrospectively explored from 2016 to 2020 for stroke hospitalizations with EVT. Outcomes were compared for EVT hospitalizations with direct vs transferred presentation at discharge. Outcomes included favorable discharge disposition (home without assistance); in‐hospital mortality; and radiographic intracranial hemorrhage (ICH). Results Among 100,865 admissions with EVT, 32,685 (32.4%) presented following hospital transfer for thrombectomy. The utilization of EVT in US nearly doubled during between 2017 to 2020, and the proportion of in‐hospital transfer for EVT remained unchanged during this period. White race, higher baseline NIHSS, hospital size and status (urban teaching vs rural), and hospital location were independent predictors of transferred status for EVT. Transferred status was significantly associated with a lower likelihood of achieving favorable outcome (OR: 0.80, CI: [0.72, 0.89], P<0.001) and a higher likelihood of ICH (1.18 [1.07, 1.31], P=0.001), whereas no differences were observed in early mortality following transferred vs direct presentation mode (1.07 [0.93, 1.23], P=0.33). Conclusion Nearly one in 3 EVTs in US is performed in patients presenting following transfer from another acute care hospital. Transferred presentation status was associated with worse clinical outcomes following EVT in a real‐world setting. Future studies are needed to determine the optimal triage strategies for patients suspected of harboring large vessel occlusion strokes.
first_indexed 2024-03-07T15:39:03Z
format Article
id doaj.art-c9f9bbb5f9294064abb2d06c4feec88b
institution Directory Open Access Journal
issn 2694-5746
language English
last_indexed 2024-04-24T13:02:17Z
publishDate 2023-11-01
publisher Wiley
record_format Article
series Stroke: Vascular and Interventional Neurology
spelling doaj.art-c9f9bbb5f9294064abb2d06c4feec88b2024-04-05T10:51:56ZengWileyStroke: Vascular and Interventional Neurology2694-57462023-11-013S210.1161/SVIN.03.suppl_2.057Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.Mohammad H. Abbasi0Steven Warach1Hamidreza Saber2UT Austin Dell Medical School Texas United StatesUT Austin Dell Medical School Texas United StatesUT Austin Dell Medical School Texas United StatesIntroduction Optimal triage strategies for patients suspected of acute ischemic stroke due to large vessel occlusion remains debated. Whereas secondary analyses from randomized trials have demonstrated no differences in thrombectomy outcomes in transferred vs direct presentation strokes (1‐2), several registry based cohorts reported worse functional outcomes in those with transferred presentation mode (3‐4). We explored the US national claims database to explore trends in presentation (transferred vs direct presentation) and their outcomes for EVT hospitalizations using a nationally representative sample. Methods National Inpatient Sample database was retrospectively explored from 2016 to 2020 for stroke hospitalizations with EVT. Outcomes were compared for EVT hospitalizations with direct vs transferred presentation at discharge. Outcomes included favorable discharge disposition (home without assistance); in‐hospital mortality; and radiographic intracranial hemorrhage (ICH). Results Among 100,865 admissions with EVT, 32,685 (32.4%) presented following hospital transfer for thrombectomy. The utilization of EVT in US nearly doubled during between 2017 to 2020, and the proportion of in‐hospital transfer for EVT remained unchanged during this period. White race, higher baseline NIHSS, hospital size and status (urban teaching vs rural), and hospital location were independent predictors of transferred status for EVT. Transferred status was significantly associated with a lower likelihood of achieving favorable outcome (OR: 0.80, CI: [0.72, 0.89], P<0.001) and a higher likelihood of ICH (1.18 [1.07, 1.31], P=0.001), whereas no differences were observed in early mortality following transferred vs direct presentation mode (1.07 [0.93, 1.23], P=0.33). Conclusion Nearly one in 3 EVTs in US is performed in patients presenting following transfer from another acute care hospital. Transferred presentation status was associated with worse clinical outcomes following EVT in a real‐world setting. Future studies are needed to determine the optimal triage strategies for patients suspected of harboring large vessel occlusion strokes.https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.057
spellingShingle Mohammad H. Abbasi
Steven Warach
Hamidreza Saber
Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.
Stroke: Vascular and Interventional Neurology
title Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.
title_full Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.
title_fullStr Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.
title_full_unstemmed Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.
title_short Abstract 057: Recent Trends and Outcomes of Hospital Transfer for Endovascular Stroke Treatment in U.S.
title_sort abstract 057 recent trends and outcomes of hospital transfer for endovascular stroke treatment in u s
url https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.057
work_keys_str_mv AT mohammadhabbasi abstract057recenttrendsandoutcomesofhospitaltransferforendovascularstroketreatmentinus
AT stevenwarach abstract057recenttrendsandoutcomesofhospitaltransferforendovascularstroketreatmentinus
AT hamidrezasaber abstract057recenttrendsandoutcomesofhospitaltransferforendovascularstroketreatmentinus