Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms

The recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmenta...

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Main Authors: Antonio Starcevic, Jurica Zucko, Juan Diego Rojas, Janko Diminic, Damir Baranasic, Ranko Gacesa, Gabriel Padilla, Paul F. Long, John Cullum, Daslav Hranueli
Format: Article
Language:English
Published: University of Zagreb Faculty of Food Technology and Biotechnology 2013-01-01
Series:Food Technology and Biotechnology
Subjects:
Online Access:http://hrcak.srce.hr/file/146488
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author Antonio Starcevic
Jurica Zucko
Juan Diego Rojas
Janko Diminic
Damir Baranasic
Ranko Gacesa
Gabriel Padilla
Paul F. Long
John Cullum
Daslav Hranueli
author_facet Antonio Starcevic
Jurica Zucko
Juan Diego Rojas
Janko Diminic
Damir Baranasic
Ranko Gacesa
Gabriel Padilla
Paul F. Long
John Cullum
Daslav Hranueli
author_sort Antonio Starcevic
collection DOAJ
description The recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmental protection. In this minireview, the current state of the field is described and the role of synthetic biology in biotechnology in the short and medium term is discussed. It is particularly aimed at the needs of food technologists, nutritionists and other biotechnologists, who might not be aware of the potential significance of synthetic biology to the research and development in their fields. The potential of synthetic biology to produce interesting new polyketide compounds is discussed in detail.
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spelling doaj.art-ca002933408a4464a5b3ae36a1455d682023-12-02T09:15:05ZengUniversity of Zagreb Faculty of Food Technology and BiotechnologyFood Technology and Biotechnology1330-98621334-26062013-01-01511311Synthetic Biology: A Novel Approach for the Construction of Industrial MicroorganismsAntonio Starcevic0Jurica Zucko1Juan Diego Rojas2Janko Diminic3Damir Baranasic4Ranko Gacesa5Gabriel Padilla6Paul F. Long7John Cullum8Daslav Hranueli9Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaInstitute of Biomedical Sciences, University of São Paulo, São Paulo SP-CEP 05508-900, BrasilFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaInstitute of Biomedical Sciences, University of São Paulo, São Paulo SP-CEP 05508-900, BrasilKing’s College, University of London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UKDepartment of Genetics, University of Kaiserslautern, Postfach 3049, DE-67653 Kaiserslautern, GermanyFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaThe recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmental protection. In this minireview, the current state of the field is described and the role of synthetic biology in biotechnology in the short and medium term is discussed. It is particularly aimed at the needs of food technologists, nutritionists and other biotechnologists, who might not be aware of the potential significance of synthetic biology to the research and development in their fields. The potential of synthetic biology to produce interesting new polyketide compounds is discussed in detail.http://hrcak.srce.hr/file/146488molecular biotechnologyindustrial microorganismsDNA synthesishomologous recombination, recombinant gene clusters
spellingShingle Antonio Starcevic
Jurica Zucko
Juan Diego Rojas
Janko Diminic
Damir Baranasic
Ranko Gacesa
Gabriel Padilla
Paul F. Long
John Cullum
Daslav Hranueli
Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
Food Technology and Biotechnology
molecular biotechnology
industrial microorganisms
DNA synthesis
homologous recombination
, recombinant gene clusters
title Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_full Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_fullStr Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_full_unstemmed Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_short Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_sort synthetic biology a novel approach for the construction of industrial microorganisms
topic molecular biotechnology
industrial microorganisms
DNA synthesis
homologous recombination
, recombinant gene clusters
url http://hrcak.srce.hr/file/146488
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