SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions
SCMNPs@Uridine/Zn is utilized as an environmental-friendly and efficient heterogeneous nanocatalyst for two one-pot four-component condensation reactions, containing hydrazine hydrate, arylaldehyde, ethyl acetoacetate, and barbituric acid to yield tricyclic fused pyrazolopyranopyrimidine derivatives...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2020-06-01
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| Series: | Polish Journal of Chemical Technology |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/pjct-2020-0013 |
| _version_ | 1818577672485208064 |
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| author | Wei Jia Gui Wenjun Cui Yanjun Zhang Zhifang Yousif Qahtan A. |
| author_facet | Wei Jia Gui Wenjun Cui Yanjun Zhang Zhifang Yousif Qahtan A. |
| author_sort | Wei Jia |
| collection | DOAJ |
| description | SCMNPs@Uridine/Zn is utilized as an environmental-friendly and efficient heterogeneous nanocatalyst for two one-pot four-component condensation reactions, containing hydrazine hydrate, arylaldehyde, ethyl acetoacetate, and barbituric acid to yield tricyclic fused pyrazolopyranopyrimidine derivatives (5a-q), and hydrazine hydrate, arylaldehyde, malononitrile, and dimethyl acetylenedicarboxylate/diethyl acetylenedicarboxylate to yield 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives (8a-y) under solvent-free conditions with high to excellent yields. The main advantages of this process are easy work-up, short reaction times, no chromatographic purifications, and recyclability of the catalyst for a minimum of six runs without any significant decrease in yields of the products. Also, the prepared catalyst SCMNPs@Uridine/Zn was synthesized and fully characterized by various techniques including Fourier transform infrared spectroscopy (FT-IR), energy dispersive X-ray (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and Raman spectroscopy. |
| first_indexed | 2024-12-16T06:33:38Z |
| format | Article |
| id | doaj.art-ca068584ba8c43649dc77ea6a11d531b |
| institution | Directory Open Access Journal |
| issn | 1899-4741 |
| language | English |
| last_indexed | 2024-12-16T06:33:38Z |
| publishDate | 2020-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Polish Journal of Chemical Technology |
| spelling | doaj.art-ca068584ba8c43649dc77ea6a11d531b2022-12-21T22:40:51ZengSciendoPolish Journal of Chemical Technology1899-47412020-06-01222203310.2478/pjct-2020-0013pjct-2020-0013SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditionsWei Jia0Gui Wenjun1Cui Yanjun2Zhang Zhifang3Yousif Qahtan A.4Gansu Agricultural University, Institute of Agricultural Resources Chemistry and Application, College of Science, Gansu Province, 730000, ChinaGansu Agricultural University, Institute of Agricultural Resources Chemistry and Application, College of Science, Gansu Province, 730000, ChinaGansu Agricultural University, Institute of Agricultural Resources Chemistry and Application, College of Science, Gansu Province, 730000, ChinaGansu Agricultural University, Institute of Agricultural Resources Chemistry and Application, College of Science, Gansu Province, 730000, ChinaUniversity of Al-Qadisiyah, College of Science, Department of Chemistry, Republic of IraqSCMNPs@Uridine/Zn is utilized as an environmental-friendly and efficient heterogeneous nanocatalyst for two one-pot four-component condensation reactions, containing hydrazine hydrate, arylaldehyde, ethyl acetoacetate, and barbituric acid to yield tricyclic fused pyrazolopyranopyrimidine derivatives (5a-q), and hydrazine hydrate, arylaldehyde, malononitrile, and dimethyl acetylenedicarboxylate/diethyl acetylenedicarboxylate to yield 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives (8a-y) under solvent-free conditions with high to excellent yields. The main advantages of this process are easy work-up, short reaction times, no chromatographic purifications, and recyclability of the catalyst for a minimum of six runs without any significant decrease in yields of the products. Also, the prepared catalyst SCMNPs@Uridine/Zn was synthesized and fully characterized by various techniques including Fourier transform infrared spectroscopy (FT-IR), energy dispersive X-ray (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and Raman spectroscopy.https://doi.org/10.2478/pjct-2020-0013nanocatalystsynthesis of tricycliccarboxylateefficient heterogeneous |
| spellingShingle | Wei Jia Gui Wenjun Cui Yanjun Zhang Zhifang Yousif Qahtan A. SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions Polish Journal of Chemical Technology nanocatalyst synthesis of tricyclic carboxylate efficient heterogeneous |
| title | SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions |
| title_full | SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions |
| title_fullStr | SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions |
| title_full_unstemmed | SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions |
| title_short | SCMNPs@Uridine/Zn: An efficient and reusable heterogeneous nanocatalyst for the rapid one-pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3-methyl carboxylate substituted pyrano[2,3-c]pyrazole derivatives under solvent-free conditions |
| title_sort | scmnps uridine zn an efficient and reusable heterogeneous nanocatalyst for the rapid one pot synthesis of tricyclic fused pyrazolopyranopyrimidine and 3 methyl carboxylate substituted pyrano 2 3 c pyrazole derivatives under solvent free conditions |
| topic | nanocatalyst synthesis of tricyclic carboxylate efficient heterogeneous |
| url | https://doi.org/10.2478/pjct-2020-0013 |
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