Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center
Background: Remote reporting in anatomic pathology is an important advantage of digital pathology that has not been much explored. The COVID-19 pandemic has provided an opportunity to explore this important application of digital pathology system in a tertiary care cancer center to ensure patient ca...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Journal of Pathology Informatics |
| Subjects: | |
| Online Access: | http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2021;volume=12;issue=1;spage=20;epage=20;aulast=Ramaswamy |
| _version_ | 1818263924646084608 |
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| author | Veena Ramaswamy B N Tejaswini Sowmya B Uthaiah |
| author_facet | Veena Ramaswamy B N Tejaswini Sowmya B Uthaiah |
| author_sort | Veena Ramaswamy |
| collection | DOAJ |
| description | Background: Remote reporting in anatomic pathology is an important advantage of digital pathology that has not been much explored. The COVID-19 pandemic has provided an opportunity to explore this important application of digital pathology system in a tertiary care cancer center to ensure patient care and staff safety. Regulatory guidelines have been described for remote reporting following the pandemic. Herein, we describe our experience of validation of digital pathology workflow for remote reporting to encourage pathologists to utilize this facility which opens door for multiple, multidisciplinary collaborations. Objective: To demonstrate the validation and the operational feasibility of remote reporting using a digital pathology system. Materials and Methods: Our retrospective validation included whole-slide images (WSIs) of 60 cases of histopathology and 20 cases each of frozen sections and a digital image-based breast algorithm after a washout period of 3 months. Three pathologists with different models of consumer-grade laptops reviewed the cases remotely to assess the diagnostic concordance and operational feasibility of the modified workflow. The slides were digitized on a USFDA-approved Philips UFS 300 scanner at ×40 resolution (0.25 μm/pixel) and viewed on the Image Management System through a web browser. All the essential parameters were reported for each case. After successful validation, 886 cases were reported remotely from March 29, 2020, to June 30, 2020, prospectively. Light microscopy formed the gold standard reference in remote reporting. Results: 100% major diagnostic concordance was observed in the validation of remote reporting in the retrospective and prospective studies using consumer-grade laptops. The deferral rate was 0.34%. 97.6% of histopathology and 100% of frozen sections were signed out within the turnaround time. Network speed and a lack of virtual private network did not significantly affect the study. Conclusion: This study of validation and reporting of complete pathology cases remotely, including their operational feasibility during a public health emergency, proves that remote sign-out using a digital pathology system is not inferior to WSIs on medical-grade monitors and light microscopy. Such studies on remote reporting open the door for the use of digital pathology for interinstitutional consultation and collaboration: Its main intended use. |
| first_indexed | 2024-12-12T19:26:45Z |
| format | Article |
| id | doaj.art-ca06a21ef4c7499d896193b97e73c4c3 |
| institution | Directory Open Access Journal |
| issn | 2153-3539 2153-3539 |
| language | English |
| last_indexed | 2024-12-12T19:26:45Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pathology Informatics |
| spelling | doaj.art-ca06a21ef4c7499d896193b97e73c4c32022-12-22T00:14:30ZengElsevierJournal of Pathology Informatics2153-35392153-35392021-01-01121202010.4103/jpi.jpi_109_20Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer centerVeena RamaswamyB N TejaswiniSowmya B UthaiahBackground: Remote reporting in anatomic pathology is an important advantage of digital pathology that has not been much explored. The COVID-19 pandemic has provided an opportunity to explore this important application of digital pathology system in a tertiary care cancer center to ensure patient care and staff safety. Regulatory guidelines have been described for remote reporting following the pandemic. Herein, we describe our experience of validation of digital pathology workflow for remote reporting to encourage pathologists to utilize this facility which opens door for multiple, multidisciplinary collaborations. Objective: To demonstrate the validation and the operational feasibility of remote reporting using a digital pathology system. Materials and Methods: Our retrospective validation included whole-slide images (WSIs) of 60 cases of histopathology and 20 cases each of frozen sections and a digital image-based breast algorithm after a washout period of 3 months. Three pathologists with different models of consumer-grade laptops reviewed the cases remotely to assess the diagnostic concordance and operational feasibility of the modified workflow. The slides were digitized on a USFDA-approved Philips UFS 300 scanner at ×40 resolution (0.25 μm/pixel) and viewed on the Image Management System through a web browser. All the essential parameters were reported for each case. After successful validation, 886 cases were reported remotely from March 29, 2020, to June 30, 2020, prospectively. Light microscopy formed the gold standard reference in remote reporting. Results: 100% major diagnostic concordance was observed in the validation of remote reporting in the retrospective and prospective studies using consumer-grade laptops. The deferral rate was 0.34%. 97.6% of histopathology and 100% of frozen sections were signed out within the turnaround time. Network speed and a lack of virtual private network did not significantly affect the study. Conclusion: This study of validation and reporting of complete pathology cases remotely, including their operational feasibility during a public health emergency, proves that remote sign-out using a digital pathology system is not inferior to WSIs on medical-grade monitors and light microscopy. Such studies on remote reporting open the door for the use of digital pathology for interinstitutional consultation and collaboration: Its main intended use.http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2021;volume=12;issue=1;spage=20;epage=20;aulast=Ramaswamyconsumer-grade laptopcovid-19image management systemlaboratory information systemlocal area networkquality controlremote reportingvirtual private networkwhole-slide image |
| spellingShingle | Veena Ramaswamy B N Tejaswini Sowmya B Uthaiah Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center Journal of Pathology Informatics consumer-grade laptop covid-19 image management system laboratory information system local area network quality control remote reporting virtual private network whole-slide image |
| title | Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center |
| title_full | Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center |
| title_fullStr | Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center |
| title_full_unstemmed | Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center |
| title_short | Remote reporting during a pandemic using digital pathology solution: Experience from a tertiary care cancer center |
| title_sort | remote reporting during a pandemic using digital pathology solution experience from a tertiary care cancer center |
| topic | consumer-grade laptop covid-19 image management system laboratory information system local area network quality control remote reporting virtual private network whole-slide image |
| url | http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2021;volume=12;issue=1;spage=20;epage=20;aulast=Ramaswamy |
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