Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis

Introduction: Retrograde intrarenal surgery (RIRS) alongside percutaneous surgery is gaining a leading position in the nephrolithiasis treatment. According to 2022 EAU Guidelines, RIRS is one of the basic surgical modalities to treat 10-20 mm kidney concrements. Turning concrements into dust, holmiu...

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Main Authors: V. V. Sergeev, V. L. Medvedev, S. A. Gabriel, V. V. Churbakov
Format: Article
Language:Russian
Published: Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1 2023-03-01
Series:Инновационная медицина Кубани
Subjects:
Online Access:https://www.innovmedkub.ru/jour/article/view/631
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author V. V. Sergeev
V. L. Medvedev
S. A. Gabriel
V. V. Churbakov
author_facet V. V. Sergeev
V. L. Medvedev
S. A. Gabriel
V. V. Churbakov
author_sort V. V. Sergeev
collection DOAJ
description Introduction: Retrograde intrarenal surgery (RIRS) alongside percutaneous surgery is gaining a leading position in the nephrolithiasis treatment. According to 2022 EAU Guidelines, RIRS is one of the basic surgical modalities to treat 10-20 mm kidney concrements. Turning concrements into dust, holmium laser is the most effective and safest method for concrement disintegration.Objective: To determine surgical possibilities of holmium laser lithotripsy for single and multiple unilateral nephrolithiasis using disposable flexible ureterorenoscopes.Materials and methods: We performed 124 interventions from October 2021 to October 2022 using LithoVue flexible ureterorenoscope in patients with nephrolithiasis, of them 70 males and 54 females with the mean age being 54 (27–74) years. Patients were divided into 2 groups: group I (56 patients) with a single renal concrement, group II (68 patients) with multiple concrements (2 to 7 pieces). The concrement size ranged from 5 to 20 mm. The density of kidney concrements on computed tomography (CT) was 214 to 1,620 HU. LightTrail 230 μm and 270 μm reusable laser fibers were chosen for Auriga XL holmium laser crushing mode. Laser operating settings were as follows: frequency 8 Hz, pulse energy 1,200 mJ (LightTrail 230 µm) and frequency 12 Hz, pulse energy 1,800 mJ (LightTrail 270 µm). These are the maximum setting values for the specific laser fibers.Results: Average time of 1 concrement disintegration (V = 1 cm3) was 28.3 minutes. Concrement disintegration time was 21.4 ± 6.7 minutes (group I) and 42.3 ± 9.4 minutes (group II). Intervention time was 27.4 ± 8.3 minutes (group I) and 54.6 ± 12.4 minutes (group II). In-hospital stay was 2.5 ± 1 days (group I) and 3 ± 1 days (group II). The rate of surgical success according to CT scans was 92.6% (group I) and 88.2% (group II). Two patients in group I and 5 patients in group II required reintervention. One patient (1.8%) in group I and 3 patients (4.4%) in group II developed an acute pyelonephritis (Clavien-Dindo classification, grade II). In the remaining patients the complications did not exceed Clavien-Dindo grade I. There were no equipment-related issues in the perioperative period.Conclusions: As a safe and effective procedure with low complication rate, fast postoperative recovery, and short hospital stay, RIRS can be used as a method of choice for disintegration of kidney concrements up to 20 mm in size.
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spelling doaj.art-ca07517f3e634cee9c6f28f489079acc2025-02-28T14:50:42ZrusScientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1Инновационная медицина Кубани2541-98972023-03-0101465210.35401/2541-9897-2023-26-1-46-52360Our Experience With Retrograde Intrarenal Surgery for NephrolithiasisV. V. Sergeev0V. L. Medvedev1S. A. Gabriel2V. V. Churbakov3Regional Clinical Hospital No. 2Kuban State Medical University; Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1Kuban State Medical University; Regional Clinical Hospital No. 2Regional Clinical Hospital No. 2Introduction: Retrograde intrarenal surgery (RIRS) alongside percutaneous surgery is gaining a leading position in the nephrolithiasis treatment. According to 2022 EAU Guidelines, RIRS is one of the basic surgical modalities to treat 10-20 mm kidney concrements. Turning concrements into dust, holmium laser is the most effective and safest method for concrement disintegration.Objective: To determine surgical possibilities of holmium laser lithotripsy for single and multiple unilateral nephrolithiasis using disposable flexible ureterorenoscopes.Materials and methods: We performed 124 interventions from October 2021 to October 2022 using LithoVue flexible ureterorenoscope in patients with nephrolithiasis, of them 70 males and 54 females with the mean age being 54 (27–74) years. Patients were divided into 2 groups: group I (56 patients) with a single renal concrement, group II (68 patients) with multiple concrements (2 to 7 pieces). The concrement size ranged from 5 to 20 mm. The density of kidney concrements on computed tomography (CT) was 214 to 1,620 HU. LightTrail 230 μm and 270 μm reusable laser fibers were chosen for Auriga XL holmium laser crushing mode. Laser operating settings were as follows: frequency 8 Hz, pulse energy 1,200 mJ (LightTrail 230 µm) and frequency 12 Hz, pulse energy 1,800 mJ (LightTrail 270 µm). These are the maximum setting values for the specific laser fibers.Results: Average time of 1 concrement disintegration (V = 1 cm3) was 28.3 minutes. Concrement disintegration time was 21.4 ± 6.7 minutes (group I) and 42.3 ± 9.4 minutes (group II). Intervention time was 27.4 ± 8.3 minutes (group I) and 54.6 ± 12.4 minutes (group II). In-hospital stay was 2.5 ± 1 days (group I) and 3 ± 1 days (group II). The rate of surgical success according to CT scans was 92.6% (group I) and 88.2% (group II). Two patients in group I and 5 patients in group II required reintervention. One patient (1.8%) in group I and 3 patients (4.4%) in group II developed an acute pyelonephritis (Clavien-Dindo classification, grade II). In the remaining patients the complications did not exceed Clavien-Dindo grade I. There were no equipment-related issues in the perioperative period.Conclusions: As a safe and effective procedure with low complication rate, fast postoperative recovery, and short hospital stay, RIRS can be used as a method of choice for disintegration of kidney concrements up to 20 mm in size.https://www.innovmedkub.ru/jour/article/view/631retrograde intrarenal surgeryconcrementholmium laserureterorenoscopelaser fibers
spellingShingle V. V. Sergeev
V. L. Medvedev
S. A. Gabriel
V. V. Churbakov
Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis
Инновационная медицина Кубани
retrograde intrarenal surgery
concrement
holmium laser
ureterorenoscope
laser fibers
title Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis
title_full Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis
title_fullStr Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis
title_full_unstemmed Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis
title_short Our Experience With Retrograde Intrarenal Surgery for Nephrolithiasis
title_sort our experience with retrograde intrarenal surgery for nephrolithiasis
topic retrograde intrarenal surgery
concrement
holmium laser
ureterorenoscope
laser fibers
url https://www.innovmedkub.ru/jour/article/view/631
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AT vlmedvedev ourexperiencewithretrogradeintrarenalsurgeryfornephrolithiasis
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AT vvchurbakov ourexperiencewithretrogradeintrarenalsurgeryfornephrolithiasis