Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness

Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness

Abstract Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The marketed topical eye drops for DED treatment often lack bioavailability and precorneal residence time. In this study, we investigated catechol-functionalized polyzwitterion p(MPC-co-DMA), composed of 2-met...

書目詳細資料
Main Authors:	Hoang Linh Bui, Yun-Han Su, Chia-Jung Yang, Chun-Jen Huang, Jui-Yang Lai
格式:	Article
語言:	English
出版:	BMC 2024-04-01
叢編:	Journal of Nanobiotechnology
主題:	Multifunctional polyzwitterion Catechol Poly(phosphobetaine) Biomaterial nanotherapeutics Ocular dryness
在線閱讀:	https://doi.org/10.1186/s12951-024-02448-x

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