Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness

Abstract Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The marketed topical eye drops for DED treatment often lack bioavailability and precorneal residence time. In this study, we investigated catechol-functionalized polyzwitterion p(MPC-co-DMA), composed of 2-met...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hoang Linh Bui, Yun-Han Su, Chia-Jung Yang, Chun-Jen Huang, Jui-Yang Lai
التنسيق: مقال
اللغة:English
منشور في: BMC 2024-04-01
سلاسل:Journal of Nanobiotechnology
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1186/s12951-024-02448-x

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