Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness
Abstract Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The marketed topical eye drops for DED treatment often lack bioavailability and precorneal residence time. In this study, we investigated catechol-functionalized polyzwitterion p(MPC-co-DMA), composed of 2-met...
المؤلفون الرئيسيون: | Hoang Linh Bui, Yun-Han Su, Chia-Jung Yang, Chun-Jen Huang, Jui-Yang Lai |
---|---|
التنسيق: | مقال |
اللغة: | English |
منشور في: |
BMC
2024-04-01
|
سلاسل: | Journal of Nanobiotechnology |
الموضوعات: | |
الوصول للمادة أونلاين: | https://doi.org/10.1186/s12951-024-02448-x |
مواد مشابهة
-
A new approach to phosphorylation of nucleosides using oxyonium phosphobetaines as intermediates
حسب: Magdalena Materna, وآخرون
منشور في: (2023-03-01) -
Immobilization of novel synthesized phosphobetaine zwitterions on polyethersulphone (PES) hemodialysis membranes to induce hemocompatibility: Experimental, molecular docking, and ex-vivo inflammatory biomarker investigations
حسب: Ubong Eduok, وآخرون
منشور في: (2024-06-01) -
Various aspects of dryness in Serbia
حسب: Kutiel Haim, وآخرون
منشور في: (2020-01-01) -
Nanotherapeutics Plus Immunotherapy in Oncology: Who Brings What to the Table?
حسب: Elise Timon-David, وآخرون
منشور في: (2022-10-01) -
Regulating Cholesterol in Tumorigenesis: A Novel Paradigm for Tumor Nanotherapeutics
حسب: Wu H, وآخرون
منشور في: (2024-02-01)