Using Pseudoenzymes to Probe Evolutionary Design Principles of Enzymes
Enzymes are governed by unique evolutionary design principles as their catalytic sites were shown to induce long-range evolutionary conservation gradients. We have recently used a comparative bioinformatics approach to disentangle structural determinants from other possible determinants of the evolu...
मुख्य लेखकों: | , |
---|---|
स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
SAGE Publishing
2019-06-01
|
श्रृंखला: | Evolutionary Bioinformatics |
ऑनलाइन पहुंच: | https://doi.org/10.1177/1176934319855937 |